Abstract
Background: Benign breast lesions are the most common breast disease in females. This study was conducted to study the clinical profile and pattern of benign breast disease and its pathological correlation.
Methods: One hundred five females who attended the Surgery Outpatients Department in Government Doon Medical College, Dehradun, with various forms of benign breast diseases during the period from October 2017 to September 2018, were studied. Early diagnoses by doing a triple assessment like a clinical examination, FNAC or a core needle biopsy and imaging methods like ultrasonography or mammography, were made within 72 hrs from the first consultation. The clinical diagnoses were compared with final diagnosis.
Results: Out of the 105 female patients who were studied, 46.66% patients were in the age group of 21 to 30 years. 63.80% patients presented with breast lumps and fibroadenoma, accounted for 46.66% of the cases, which was the highest number of patients. Fibrocystic changes and breast abscesses came next with 29.52% and 6.66% cases respectively. The right breast was involved in 45 (42.85%) patients, and upper outer quadrant was most commonly involved (59.04%).
Conclusion: Results grossly similar to other parts of the word were obtained. Benign breast diseases are common in female patients in the second followed by third decade of their life. Breast lump is the most common presentation involving the upper outer quadrant and of all the benign breast diseases fibroadenoma is the commonest of them all. Triple assessment provided a quick diagnosis and it alleviated unnecessary anxiety from the patients about breast cancer. Breast self-examination and education to the females is required for early diagnosis and prompt treatment as majority of anxiety and worry of having breast cancer can be alleviated.
Keywords: Benign breast disease, Fibroadenoma, Fibroadenosis, Triple assessment.
References
- Shetty MK, Shah YP, Sharman RS. Prospective evaluation of the value of combined mammographic and sonographic assessment in patients with palpable abnormalities of the breast. Journal of Ultrasound in Medicine 2003;22(3):263-268.
- Moy L, Slanetz PJ, Moore R, Satija S, Yeh ED, McCarthy KA et al. Specificity of mammography and US in the evaluation of a palpable abnormality: retrospective review. Radiology 2002;225(1):176-181.
- Soo MS, Rosen EL, Baker JA, Vo TT, Boyd BA. Negative predictive value of sonography with mammography in patients with palpable breast lesions. AJR American Journal of Roentgenology 2001;177(5):1167-1170.
- Flobbe K, Bosch AM, Kessels AG, Beets GL, Nelemans PJ, von Meyenfeldt MF et al. The additional diagnostic value of ultrasonography in the diagnosis of breast cancer. Archives of Internal Medicine 2003;163(10):1194-1199.
- Smith GE, Burrows P. Ultrasound diagnosis of fibroadenoma - is biopsy always necessary?[see comment]. Clinical Radiology 516;63(5):511-515.
- Tamimi RM, Rosner B, Colditz GA. Evaluation of a breast cancer risk prediction model expanded to include category of prior benign breast disease lesion. 2010;116:4944–53. doi: 10.1002/cncr.25386.
- Cote ML, Ruterbusch JJ, Alosh B, Bandyopadhyay S, Kim E, Albashiti B, et al. Benign breast disease and the risk of subsequent breast cancer in African American women.Cancer Prev Res (Phila) 2012;5:1375–80. doi: 10.1158/1940-6207.CAPR-12-0175.
- Worsham MJ, Raju U, Lu M, Kapke A, Cheng J, Wolman SR. Multiplicity of benign breast lesions is a risk factor for progression to breast cancer.Clin Cancer Res. 2007;13:5474–9. doi: 10.1158/1078-0432.CCR-07-0928.
- Aroner SA, Collins LC, Connolly JL, Colditz GA, Schnitt SJ, Rosner BA, et al. Radial scars and subsequent breast cancer risk: Results from the Nurses' Health Studies.Breast Cancer Res Treat. 2013;139:277–85. doi: 10.1007/s10549-013-2535-9.
- Kaur Navneet, Agarwal Nitin, Parwar Pankaj. Clinicopathologic profile of benign breast conditions in Indian women. Prospective study based on aberrations of normal development and involution classification. World J Surgery. 2012; 36:2252–58. [PubMed].
- Kulkarni S, Vora I. M, Ghorpade K G, Shrivastava S: Histopathological spectrum of breast lesions with reference to uncommon cases. Obstet Gynecol India 2009; 59 (5):444-452.
- Amr SS, Abdul Rahman, M Sadi, FazalIlahi, SS Sheikh. The Spectrum of Breast Diseases in Saudi Arab Females: A 26 yr Pathological Survey at Dhahran Health Center. Ann Saudi Med 1995; 15(2):125-132.
- Malik MAN, Salahuddin O, Azhar M, Dilawar O, Irshad H, Sadia, Salahuddin A. Breast diseases; Spectrum in WahCantt; POF Hospital experience. Professional Med J Sep 2010; 17(3):366-372
- Naveen N, Avijeet M and Vikrant M.A clinical study of benign breast disease in rural population. Journal of Evolution of Medical and Dental Sciences 2013; 12:5499-511.
- Rashid R, Haq SM, Khan K, Jamal S, Khaliq T and Shah A.Benign breast disorders, a clinicopathological Study. Annals of Pakistan Institute of Medical Sciences 2005; 1:187-90.
- Khanna S, Arya NC, Khanna NN. Spectrum of benign breast disease. Indian Journal of Surgery 1988; 50 : 169-75.
- Decholnoky T. Benign tumors of the breast. Arch Surg. 1937; 38:79.
- Oluwole SF, Freeman HP. Analysis of benign breast disease lesions in blacks. Am J Surg. 1979;137:786- 9.
Corresponding Author
Dr Dinesh Singh Chauhan
Address: Government Doon Medical College and Hospital Dehradun Uttarakhand Pin 248006, India
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.