Title: Study of the severity of Diabetic Retinopathy in patients with duration of Diabetes mellitus longer than 10 years – a study from a tertiary care hospital in North- India
Authors: Abhishek Padha, Swati Sharma, Dinesh Gupta, Prateek Koul
DOI: https://dx.doi.org/10.18535/jmscr/v6i11.60
Abstract
Background: Diabetic retinopathy is one of the most common complications of Diabetes Mellitus causing significant visual loss on a global scale.
Purpose: To evaluate the severity of Diabetic retinopathy in diabetics of duration of disease longer than 10 years.
Materials and Methods: This study was conducted over a period of one year from Nov. 2015 to Oct. 2016 in a tertiary care hospital of northern India, on 100 diagnosed patients of diabetes mellitus presenting to the Ophthalmology OPD. After detailed history, clinical examination and investigations, the patients were graded on basis of severity of diabetic retinopathy. The data analysis was performed using statistical software SPSS version 20. Relationship of diabetic retinopathy (dependent variable) was assessed employing univariate analysis. Chi-square test was used to assess statistical significance.
Results: Out of the 100 patients examined, 89 were having some form of retinopathy on presentation. The mean ages of patients with mild, moderate, severe NPDR and PDR were 54.85±10.02, 60.84±8.59, 64.77±10.97, 67.76±11.71 years respectively. The mean duration of diabetes mellitus in the study for mild, moderate, severe NPDR and PDR were 14.95±4.29, 17.76±3.89, 18.66±3.69 and 24.53±5.92 years respectively. Significant correlation were seen between severity of retinopathy and duration of DM, mean HbA1c, S.Creatinine, macroalbuminuria, anaemia and hypertension.
Conclusion: This study will be significant in determining risk factors for the causation of diabetic retinopathy and its progression. It will be a useful tool in identification of the modifiable risk factors which can help in prevention and progression of diabetic retinopathy.
Keywords: Diabetes Mellitus, Diabetic Retinopathy, severity of Diabetic Retinopathy.