Abstract
Introduction: Hepatitis B virus infection cause for significant health care burden in India and now became threat like other disease – Tuberculosis, Malaria and HIV. The World Health Organization (WHO) estimates that there are 350 million people with chronic HBV infection and 170 million people with chronic HCV infection worldwide. Hepatitis B is estimated to result in 563000 deaths and hepatitis C in 366000 deaths annually.
Materials and Methods: Serum from 4,415 patients who attended Government Medical College and Hospital, Kannauj was screened for detection HBV surface Ag using the Rapid Card Diagnostic Test (Reckone Diagnostic). All rapid test positive samples were further tested by a third-generation Enzyme linked immune sorbent assay (ELISA).
Results: The overall sero-prevalence of HBV among patients was 2.28%. A high sero-positivity was prevalent in the age group of 21-30 years (0.88%).
Conclusion: The sero frequency of hepatitis is high in age group of 21-30 years attending Government Medical College and Hospital, Kannauj, Uttar Pradesh.
References
- Mujeeb SA, Aamir K, Mehmood K. Seroprevalence of HBV, HCV and HIV infections among college going first time voluntary blood donors. J Pak Med Assoc., 2002; 50(8): 269-70.
- Ali SA, Rafe MJ, Donahueb, Qureshi H, Vermunda SH. Hepatitis B and hepatitis C in Pakistan: prevalence and risk factors. Int J Infect Dis., 2009 January; 13(1): 9-19.
- Res S, Bowden FJ. Acute hepatitis B infection following a community-acquired needle stick injury. J Infect 2011;62(6): 487-9.
- Puri P. Tackling the Hepatitis B disease burden in India. J ClinExpHepatol. 2014;4(4):312–319.
- Centers for Disease Control and Prevention. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HBV, HCV, and HiV and recommendations for post exposure prophylaxis. MMWR 2001;50(RR-11):1-52.
- Puri P. Tackling the hepatitis B disease burden in India. J ClinExpHepatol 2014;4: 312–319. doi: 10.1016/j.jceh.2014.12.004
- World Health Organisation. Fact Sheet. Hepatitis B. Available from: http://www.who.int/mediacentre/factsheets/fs204/en/#
- Samaranayake L. Rule of infection control. Int Den J, 1993; 43(6): 578-84.
- Courouce AM, Lee H, Drouet J, et al. Monoclonal Antibodies to HBSAg: A Study of their Specificities for eight different Sub-types. Developments in Biological Standardization. 1983; 54: 527–34p.
- Perrillo R. Hepatitis B and D. Liver, In: Feldman M, Friedman LS, Brandt LJ (Ed.). Sleisenger and Fordtran's gastrointestinal and liver disease: Pathophysiology, diagnosis, management, Vol. II, 9th Edn. Philadelphia: Saunders; 2010. 1287–311.
- Nanu A, Sharma SP, ChatterJee K, et al. Markers for Transfusion Transmissible diseases in Northern Indian Voluntary and Replacement Blood Donors: Prevalence and Trends. Vox Sang. 1997; 73: 70–3p.
- World Health Organization. Status of blood safety in the WHO African Region. Report of the 2004 Survey WHO Regional Office for Africa, Brazzaville. Geneva: WHO; 2007.
- Torane VP, Shastri JS. Comparison of ELISA HBSAg and HCV among healthy blood donors in a tertiary Care Hospital in Mumbai. Indian J Med. Microbiol. 2008;2: 284–5p.
- Bottero J, Boyd A, Gozlan J, Lemoine M, Carrat F, Collignon A, et al. Performance of rapid tests for detection of HBsAg and Anti-HBsAb in a large cohort. France J Hepatol. 2013;58:473–8.
- Quadri SA, Dadapeer HJ, Arifulla KM, Khan N. Prevalence of hepatitis B surface antigen in hospital based population in Bijapur, Karnataka. Al Ameen J Med Sci 2013;6:180‑
- Agarwal, et al. Incidental detection of hepatitis B and C viruses and their coinfection in a hospital‑based general population in tertiary care hospital of Uttar Pradesh.Journal of Family Medicine and Primary Care. September 19, 2018, IP: 47.8.159.110
- Suhail Latoo, Mohammad Shafi, Humaira Nazir. Sero-prevalence of Hepatitis B and C virus among patients attending Dental clinics in Kashmir Valley. IAIM, 2017; 4(2): 53-59.
Corresponding Author
Sanjeev Tripathi
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DOI: https://dx.doi.org/10.18535/jmscr/v6i11.55
