Title: A Case Report of Neuromyelitis Optica Spectrum Disorders
Authors: Dr R. Guruboo Balaji, Dr S. Noorul Ameen, Prof. D. Rajasekaran
DOI: https://dx.doi.org/10.18535/jmscr/v6i11.07
Abstract
Neuromyelitis optica (NMO) and Neuromyelitis optica spectrum disorders (NMOSD) are inflammatory disorders characterized by immune-mediated demyelination and axonal damage predominantly involving optic nerves and spinal cord. Previously NMO was considered as a variant of multiple sclerosis (MS), but now it is considered a separate entity(1). Here we report a case of middle aged female presenting with quadriplegia, urinary retention, sensory abnormalities which suggested myelopathy but without any evidence of optic neuritis, suggesting a diagnosis of neuromyelitis optica spectrum disorder. The diagnosis was confirmed by positive aquaporin 4 antibody.