Title: Role of C-Reactive Protein and total Leucocyte as Diagnostic Adjuvant in Managing Acute Appendicitis
Authors: Dr N. Junior Sundresh, Dr G. Arun Chander, Dr Ashwin Muthukumar
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.214
Abstract
Abdominal pain is normally encountered in emergency department by Surgeon and commonest cause of abdominal pain is found to be appendicitis. Though diagnosis is purely clinical certain blood investigations and other modalities of investigation play a role. In this study to role of C-reactive protein and Total leucocyte count has diagnostic adjuvant in managing appendicitis is evaluated.
Methods: C-Reactive protein and total leucocyte count investigations were made for all patients with clinical suspicion of appendicitis. Post operative HPE reports is cross checked with C-Reactive proteins and white blood cell count and specificity and sensitivity were made out and statistical data analyzed.
Results: In present study Total leucocyte count has more sensitivity and specificity (95.56%, 80%), followed by C-reactive protein (88.89%, 80%).
Conclusion: When both test (Total leucocyte count & C-reactive protein) are combined the sensitivity and specificity increases significantly. It plays important role in doubtful cases for arriving diagnosis.
Keywords: Appendicitis, C-reactiove protein, Total leucocyte count.