Aims and Objectives: To study a population of 50 people in a rural tertiary care hospital with goitre presenting in surgical opd, do a thorough clinical examination, Thyroid function test, ultrasonogram of neck, Fine needle aspiration cytology, anti thyroid peroxidise titres and correlate with incidence of thyroiditis and other causes of goitre

Materials and Method: 50 people attending surgical OPD in Rajah Muthaiah Medical college hospital presenting with goitre excluding those who are on previous management.

Results: It was found in the study that all patients of thyroiditis (hashimoto’s) and grave’s disease have increased titres of Anti TPO antibodies (thyroiditis>>grave’s) and there was no correlation between thyroid function tests and ANTI TPO antibodies.

Conclusion: As such Anti TPO antibodies can be used a tool in diagnosing thyroiditis in thyroid swellings mimicking malignancy which may otherwise need surgery as thyroiditis responds well to medical management.

1. Bailey and Love’s Short Practice of surgery.editors Williams, O’Connor and McCaskie. 27^thCRC press 2018. chapter 50.
2. Sabiston Textbook of Surgery. 20^th edn .editors Townsend. Elsiever 2016. chapter 38.

Shakthi Saravanan K V