Title: Prevalence of urinary tract pathogen and its antimicrobial susceptibility pattern in children admitted in KMCH, Katihar, Bihar and compare its susceptibility pattern from national trend
Authors: Ashit Kumar, Ghazi S. Ahmad, Kumar S. Nath, Shreshy Singh, MD Arshad Alam
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.158
Abstract
Objective: This study was conducted to determine the prevalence of organism causing UTI, effect of gender & age on its prevalence, the antimicrobial susceptibility and resistance profile of bacterial isolates and compare it from national trend.
Method: Consecutive patient with culture positive UTI were enrolled in this study.
The urine samples were processed and microbial isolates were identified by conventional methods. Antimicrobial susceptibility testing was performed on all bacterial isolates by Kirby bauer’s disc diffusion method.
Result: 73 consecutive culture positive urinary sample from May 2017 to September 2018, was analysed. Most common organism isolated is E.coli (n=36) followed by klebseilla (n=11), staphylococcus aureus (n=11), enterococcus species(n=7), candida (n=7), proteus mirabilis (n=1).Most of the E. Coli was resistant to ceftriaxone followed by amoxicillin and maximum sensitivity seen with nitrofurantoin. Maximum resistance of klebsiella was seen with amoxicillin followed by ceftriaxone. None of the staphylococcus aureus isolated in this study was sensitive to amoxicillin and maximum resistance seen with cephalexin followed by cotrimoxazole and teicoplanin.
Discussion: most common organism causing UTI comes out to be E.coli and klebsiella which shows increasing resistant to ceftriaxone and amoxicillin in pediatric age group. This necessitates the need to form regional antibiogram to guide the therapy.
Keyword: UTI (urinary tract infection), E.coli, klebsiella, staphylococcus aureus, amoxicillin, ceftriaxone.
