Title: Accuracy of Pulmonary Asthma Score in Predicting Severity of Asthma Exacerbation in Mild and Moderate Asthma
Authors: Dr R. Ramanathan, Dr B. Mahalakshmi
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.155
Abstract
Objectives: The objective of the study was to determine the accuracy of pulmonary asthma score in predicting severity of asthma exacerbation and comparison of efficacy between levosalbutamol and ipratropium combination over levosalbutamol nebulization in reversing airflow obstruction and improving oxygenation, evaluated using the pulmonary asthma score, SaO2, and PEFR in mild and moderate asthma.
Methods: A prospective, randomized, study was performed in RMMCH pediatric emergency department. Children between 6 and 12 years of age who presented with mild to moderate asthma exacerberations were included in the study. They were randomly allocated into two different groups: one nebulized with levosalbutamol alone and another with addition of ipratropium bromide to levosalbutamol. Baseline Peak expiratory flow rate and final absolute values or change from baseline 60–120 minutes after the inhalation are measured. Patients were evaluated using the pulmonary asthma score4.
Results: After treatment there is improvement in the mean pulmonary asthma scores and PEFR percentage in A+B group than A group, but it is not statistically significant (p value >0.05). There is statistically significant improvement in pulmonary asthma score and PEFR in each of the groups before and after nebulization and pulmonary asthma score has a sensitivity of 66.7% and 65.6% in diagnosing severity of asthma in relation to PEFR.
Keywords: Levosalbutamol, Ipratropium bromide, peak expiratory flow rate, pulmonary asthma score (PAS).
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