Abstract
Neurological manifestations of hypothyroidism are not usually seen early in the course of the disease, particularly muscle disease. Entrapment neuropathy is more common and may be a presenting symptom. Hypothyroidism presenting as muscle stiffness and pseudohypertrophy in adults is known as Hoffman’s syndrome which is supported by presence of elevated CPK and EMG features of myopathy, neuropathy or mixed pattern. With hormone replacement therapy symptoms and CPK levels normalize promptly. We report a case of hypothyroidism with extreme muscle pain, calf muscle hypertrophy as initial symptoms.
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Corresponding Author
Dr H Subramony
Consultant Physician, Apollo Hospitals, Greams Road, Chennai 600006, India
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., PH: 9841073910
DOI: https://dx.doi.org/10.18535/jmscr/v6i8.158
