Abstract
Background: Hypothyroidism is a common disorder. It may emerge or worsen other comorbidities. This study was conducted to know demographic, clinical, comorbidity and lipid profile of hypothyroid patients in Rajasthan in order to understand current scenario and to know desired improvement in strategy.
Method: This cross sectional study was conducted for the duration of six months. One hundred and three hypothyroid patients participated in the study. Thirteen patients were drop outs and ninety participated actively. These patients were evaluated for different parameters like age, sex, presence of clinical symptoms, comorbidities and lipid profile.
Results: Mean age of study population was 49 years with male female ratio 1:4. Subclinical hypothyroidism was present in 42.2% patients. Comorbidities were found in 65.5% patients. Hypertension was the most common comorbidity followed by diabetes, chronic kidney disease, coronary artery disease and stroke. Dyslipidemia was present in 71.1% patients. Most common deranged parameter was LDL followed by triglyceride, total cholesterol and HDL.
Conclusion: High percentage (42.2%) of subclinical hypothyroidism shows need of screening programme for evaluation of thyroid disorder in general population. High percentage of deranged lipid profile (71.1%) and presence of comorbidities (65.5%) warrant the need of evaluation of every hypothyroid patient to limit morbidity and mortality.
Keywords: Hypothyroidism, dyslipidemia, comorbidity.
References
- Giorda CB, Carnà P, Romeo F, Costa G, Tartaglino B, Gnavi R. Prevalence, incidence and associated comorbidities of treated hypothyroidism: an update from a European population. Eur J Endocrinal. 2017;176(5):533-542.
- Mathur N, Mathur M. A study of risk factors related to coronary vascular disease among patients attending a tertiary health care institute of Rajasthan. Inter J Sci Res. 2017;6(12):112-3.
- Mathur M, Mathur N. Stroke: Risk factors evaluation in patients attending a tertiary health care institute of Rajasthan. Paripex Ind J Res. 2017;6(12):1-3.
- Mathur M, Mathur N, Singh O, Solanki J, Soni P, Sarwa A, et al. Demographic characters and factors favouring emergence of diabetes mellitus type 2. Int J Res Med Sci. 2018;6:950-4.
- Paul J, Dasgupta S. Co-morbidities in Hypothyroid Patients in a Tertiary Health Care Hospital in India. Thyroid Disorders Ther. 2012;1:106.
- Anandhasayanam A et al. Prevalence of hypothyroidism and its co-morbidities in relation to the causes and risk factors in patients undergoing levothyroxine therapy. IJPSR, 2016;7(3):1251-1257.
- Chen WH, Chen YK, Lin CL, Yeh JH, Kao CH. Hashimoto's thyroiditis, risk of coronary heart disease, and L-thyroxine treatment: a nationwide cohort study. J Clin Endocrinol Metab.2015;100(1):109-14.
- Abdelhai AR, Salem IM, Gawish HH. Comorbidity assessment and thyroid hormones in independently-living elderly. Zagazig University Medical Journal. 2016;22(3);99-107.
- Kibria KG, Alam MR, PaulHK, Fariduddin M, Hasanad MA. Pattern of Dyslipidemia in Hypothyroid Patients -A cross sectional study. BSMMU J. 2013;6(2):156-160.
- Guntaka M, Hanmayyagari B, Rosaline M, Nagesh V. Lipid profile in subclinical hypothyroidism: A biochemical study from tertiary care hospital. CHRISMED J Health Res 2014;1:266-70.
- Asranna A, Taneja R S, Kulshreshta B. Dyslipidemia in subclinical hypothyroidism and the effect of thyroxine on lipid profile. Indian J Endocr Metab. 2012;16, Suppl S2:347-9.
Corresponding Author
Dr Medha Mathur
Department of Community Medicine, Pacific Institute of Medical Sciences, Umarda, Udaipur, India-313015
Mobile No.-9983997544, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v6i8.91
