Abstract
Sebaceous carcinoma is one of the rare malignancies encountered in clinical practice. They are very aggressive because of their pagetoid type of spread and also because of vascular and perineural invasion. With these features it forms a therapeutic challenge. Here, we present a rare case of sebaceous carcinoma in a 62 year old female with metastases in both parotid and abdomen 6 months after surgical resection of primary in the eyelid.
Keywords: Sebaceous carcinoma, Malignancy, Eyelid, Parotid.
References
- Warren S, Warvi WN. Tumors of sebaceous glands. Am J Pathol 1943; 19: 441-59.
- Tryggvason G, Bayon R, Pagedar NA. Epidemiology of sebaceous carcinoma of the head and neck: implications for lymph node management. Head Neck 2012; 34: 1765-8.
- Masson P, Gery L. Epitheliomasebace. Bull Assoc Franc 1’Etude Cancer 1922;11:284-95.
- Morton DL, Wen DR, Foshag LJ, et al. Intraoperative lymphatic mapping and selective cervical lymphadenectomy for early-stage melanomas of the head and neck. J Clin Oncol 1993;11:1751-6.
- Motley RJ, Douglas-Jones AF, Holt PJA. Sebaceous carcinoma: an unusual cause of a rapidly enlarging rhinophyma. Br J Dermatol 1991;24:283-4.
- Sara C Shalin, Stephen Lyle, Eduardo Calonje, Alexander J F Lazar. Sebaceous neoplasia and the Muir-Torre syndrome: important connections with clinical implications. Histopathology 2010,56,133-147.
- Lever WF, Schaumburg-Lever G, eds. Histopathology of the skin. 7th ed. Philadelphia: JB Lippincott, 1990:578-650.
- Bruce R Nelson, K Renee Hamlet, Timothy M Johnson. Sebaceous carcinoma. J Am AcadDermatol 11995;33:1-15.
- Kwitko ML, Boniuk M, Zimmerman LE. Eyelid tumors with reference to lesions confused with squamous cell carcinoma: I. Incidence and errors in diagnosis. Arch Ophthalmol 1963;69:696-7.
- Narita H, Kanzaki T, Yokota M, et al. Muir-Torre syndrome. J Dermatol 1992;19:105-8.
- Ginsberg J. Present status of Meibomian gland carcinoma. Arch Ophthalmol 1965;73:271-7.
- Pardo FS, Wang CC, Albert D, et al. Sebaceous carcinoma of the ocular adnexa: radiotherapeutic management. Int J Radiat Oncol Biol Phys 1989;17:643-7.
- Paschal BR, Bagley CS. Sebaceous gland carcinoma of the eyelid: complete response to sequential combination chemotherapy. N C Med J 1985;46:473.
- Priyadarshini O, Biswas G, Biswas S, Padhi R, Rath S. Neoadjuvant chemotherapy in recurrent sebaceous carcinoma of eyelid with orbital invasion and regional lymphadenopathy. Ophthal Plast Reconstr Surg. 2010;26:366–368.
Corresponding Author
Praneeth Kumar Koduru
DNB Postgraduate Trainee, Department of ENT,
Downtown Hospital, Guwahati, Assam, India