Abstract
Background: Which form of tobacco use has more adverse effects on lipid profile?
Objective: To identify the effect of tobacco use as smoking or chewing is associated with greater adverse effects on various components of serum lipid profile.
Materials and Methods: The study was conducted on 400 subjects (200 tobacco smoker & 200 tobacco chewer) admitted in wards and attending OPD under department of medicine, NIMS medical college & hospital Jaipur and 400 controls. S. Cholesterol by enzymatic end point CHOD/PAP method. S. Triglyceride by enzymatic glycerol phosphate oxidase/peroxidase method S. HDL by homogenous enzyme direct assay. Statistical analysis was done using SPSS Ver. 20 (IBM SPSS Statistical Inc., Chicago, Illinois, USA). The independent t test and ANOVA with post hoc Bonferroni test were used for comparison of all clinical indicators. Chi – square test used for qualitative data whenever two or more than two groups were used to compare. Level of significance was set at P≤0.05.
Results: Mean value of TC, TG, LDL, VLDL, of tobacco smokers and tobacco chewers were found significantly higher (P<0.001) as compared to mean values of these parameters amongst non smokers, non chewers. The mean HDL amongst tobacco smokers was significantly lower as compared to controls.
Conclusion: Tobacco is the major preventable risk factor for atherosclerosis related clinical events like coronary artery disease. Cigarette smoking had greater adverse effects on the serum lipid profile as compared to bidi smoking and tobacco chewing thereby increasing the cardiovascular risk.
Keywords: Tobacco, Lipid profile, Cigarette smoke, Tobacco Chewing.
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Corresponding Author
Manju Pandey
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DOI: https://dx.doi.org/10.18535/jmscr/v6i7.143
