Abstract

Objective: To study the effect of Nagaradi Kashayadrug on biochemical parameters and clinical symptoms among the patients of Ashmari (urolithiasis).

Methods: This was a clinical trial. Patients suffering from silent features of Mutrashmari were included in the study. Nagaradi Kashaya Kwath was administered in the eligible patients full filling the criteria of selection, in the dose of 40ml each twice daily for 1 month. Biochemical parameters and signs and symptoms were assessed before and after treatment.

Results: The significant (p=0.001) effect of drug was found only on urea which was 26.80±3.65 before treatment and became 25.20±3.98 after treatment. There was no significant (p>0.05) effect the drug on other biochemical parameters. Low back ache was significantly (p=0.001) decreased from before treatment (70%) to after treatment (66.7%). Intermittent colicky pain was also significantly (p=0.02) decreased from before treatment (56.7%) to after treatment (52.9%). There was significant improvement in most of the symptoms from before treatment to after treatment.

Conclusion: It can be concluded that Nagaradi kashaya possesses the properties regarding in relief in sign and symptoms of Mutrashmari which proves that it is an ideal preparation for the management of Mutrashmari. If the duration of trial would have been increased, we might find some positive finding regarding kidney stones too.

Keywords: Ashmari, Clinical symptoms, Nagaradi kashaya.