Abstract
Introduction: Salivary gland lesions are the most commonly involved head and neck swellings ranging from reactive inflammatory to neoplastic, which may be benign or malignant.Though histopathological diagnosis is gold standard for confirmation of fine needle aspiration cytology (FNAC) findings, FNAC is an excellent first-line tool in providing an early diagnosis.
Aims and Objectives: To elucidate the cytomorphological features of various salivary gland lesions on FNAC and explore the diagnostic criteria by correlating with histomorphological findings.
Materials and Methods: The present study was done at the Department of Pathology, Sri Manakula Vinayagar Medical College, Pondicherry. FNAC was done using 24 gauge needle and 5 ml syringe and smears were stained with Haematoxylin & Eosin (H&E) and Giemsa stains. Histopathology was assessed on routine H&E stained paraffin sections. Cyto-histo correlation was done and overall diagnostic accuracy was calculated.
Result: The accuracy of FNAC in diagnosing salivary gland lesions was 72%.Age group between 51-60yrs was found to be the most common for salivary gland lesions and parotid was found to be the most common site for salivary gland lesions.
Conclusion: From this study it was concluded that fine needle aspiration cytology is an excellent first line of investigation for the diagnosis of various salivary gland lesions. However, there still remain few diagnostic dilemmas in which histopathology and immunohistochemistry confirmation is required.
Keywords: Diagnostic accuracy, FNAC, histopathology, salivary gland lesions, sensitivity, specificity.
References
- Donahue BJ, Cruickshank JC & Bishop JW. The diagnostic value of fine needle aspiration biopsy of head and neck masses.ENT Journal.1995; 74(7): 483 -6.
- Wilson JA, McIntyre MA, VononHaacke P et al. Fine needle aspiration biopsy and the otolaryngologist. The Journal of Laryngology and Otology. 1987; 101(6): 595-600.
- Lumley JSP, Chan S, Harris H, Zangana MOM. Physical signs. 18th edition. Oxford: Butterworth-Heinemann, Oxford, 1997.
- Tessy PJ, Jayalekshmy PS, Cicy PJ, Usha P. Fine needle aspiration cytology of salivary gland lesions with histopathological correlation. Int J Healthc Biomedical Res, 2015;4(3):91-9.
- Kakoty S, Baruah TD, Babu CPG. FNAC and histopathological correlation of salivary gland lesions: an observational study. IntSurg J 2017;4:2148-52.
- Thangam R, Vaishali DK, Dhananjay SK, Koteeswaran G, Kannan NS. Cytological and Histomorphological Correlation of Salivary Gland Lesions. APALM, 2017;4(2):219-23.
- Winifred G,Gabrijela K. Diagnostic Cytopathology, 3rd edition. Elsevier.
- Gunvanti B Rathod, PragneshParmar. Indian Journal Of Medical Sciences, Vol. 66, No. 3 And 4, March And April 2012.
- Koss, Leopold G, Melamed, Myron R. Koss' Diagnostic Cytology and Its Histopathologic Bases, 5th edition. Lippincott Williams & Wilkins. Vol II.
- Qizilbash AH, Sainos J, Young JEM, et al. Fine needle aspiration biopsy cytology of major salivary glands. ActaCytologica 1985;29:503-12.
- O'Dwyer P, Farrar WB, James AG, Finkelmeier W, McCabe DP. Needle aspiration biopsy of major salivary gland tumors. Its value. Cancer. 1986 Feb 1;57(3):554–557.
- Jayaram, N., Ashim, D., Rajwanshi, A., Radhika, S. and Banerjee, C. K. (1989), The value of fine-needle aspiration biopsy in the cytodiagnosis of salivary gland lesions. Diagnostic Cytopathology, 5: 349–354.
- Shintani S, Matsuura H, Hasegawa Y (1997) Fine needle aspiration of salivary gland tumors. Internet Journal of Oral Maxillofacial Surgery 26:284–286.
- Tandon S, Shahab R, Benton JI, Ghosh SK, Sheard J, Jones TM. Fine-needle aspiration cytology in a regional head and neck cancer center: comparison with a systematic review and meta-analysis. Head and Neck. 2008;30(9):1246-52.
- Savithri Chauhan, Dimple D, Dholakia A. Fine needle aspiration cytology of neck lesion – An experience at tertiary care hospital in central Gujarat. National journal of medical research. 2012;2(3): 255-9.
- Rajbhandari et al. The correlation between fine needle aspiration cytology and histopathology of head and neck lesions in Kathmandu University Hospital. Kathmandu University Medical Journal (KUMJ). 2013 Oct-Dec;11(44):296-9.
Corresponding Author
Dr V. Sriram
Assistant Professor, Department of Pathology, Sri Manakula Vinayagar Medical College and Hospital
Kalitheerthalkuppam, Puducherry, 605107
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mob 9500993884