Abstract
Chronic renal failure (CRF) is a state which results from a permanent and usually progressive reduction in renal function. Chronic renal failure (CRF) is also known as chronic kidney disease (CKD). Chronic kidney disease (CKD) is a long term condition caused by damage to both kidneys. Patients with chronic kidney disease (CKD) are at an increased risk for cardiovascular disease and have a higher prevalence of hyperlipidaemia. Most characteristic lipid abnormality are increased level of serum triglycerides, very low density lipoprotein (VLDL), and low levels of high density lipoprotein. A total of 50 patients having CKD was compared by the same no. Of control group individuals. Manual methods were used to detected the abnormalities in Lipid Panel. All the Parameter of Lipid Panel were significantly raised such as TG, Cholesterol, LDL-Cholesterol, etc. As comparied with that of control group. Conclusion of the study that there is significant dyslipidemia, raised in chronic renal failure patients as compared to healthy controls. Higher urea, creatinine, uric acid correlates well with development of chronic renal failure. So, It gives us a clue regarding possible metabolic relation in chronic renal failure patient. Hence, this study has been a step forward to find relation of multiple metabolic factors with chronic renal failure and raises a fundamental issue of need of further research in this direction which can help in better understanding of this disease and in developing new therapeutic strategies in treatment of chronic renal failure patients.
Keywords: CKD, Cholesterol, TG, HDL, LDL.
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Corresponding Author
Dr Pankaj Kumar Meena
Biochemist, Department of Biochemistry
NIMS Medical College, Jaipur
DOI: https://dx.doi.org/10.18535/jmscr/v6i7.14
