Abstract
Migraine is the most common neurological disorder; on molecular basis it is still not completely understood. An impairment of mitochondrial oxidative metabolism might play a role in the pathophysiology. The aim of this present study was to investigate the differences in oxidative stress status with the measurement of glutathione reductase (GR), glutathione peroxidase (GPx), Superoxide dismutase (SOD), glutathione -s- transferase (GST) and total antioxidant (TAS). There were 110 patients selected in the migraine group and 50 age matched healthy subjects were selected in control group. It shows that the levels of GR, GPx, GST, SOD and total antioxidant were significantly decreased found in migraine patients before treatment compare to normal group as well as after treatment.
Keywords: Migraine, OS, NO, rTMS, AMT, GST, GSH, MDA, SOD and TAS.
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Corresponding Author
Dr Pradeep Kumar Shukla
Assistant Professor Dept. of Medicine, Santosh Medical College Ghaziabad, India
DOI: https://dx.doi.org/10.18535/jmscr/v6i5.184
