Abstract
Introduction
Dengue is a mosquito borne viral disease caused by Dengue virus (DEN-1, 2, 3&4). Dengue is endemic in more than 100 countries[1]. Dengue constitutes a major cause of pediatric morbidity and mortality in South East Asian countries[2]. Dengue fever (DF) has been reported from India over a longtime, but dengue hemorrhagic fever (DHF) was first reported in 1963 from Calcutta city[3]. Since then several outbreaks of dengue fever have been reported from India with a major epidemic of dengue hemorrhagic fever that occurred in Delhi in 1996 when 10,252cases and 423 deaths were reported[3]. Manifestation in children and adults differ in many ways. In a study, children had higher proportion of DHF I (42.9%) cases, whereas 51% adults were of DHF II. Some clinical manifestations, such as petechiae, melena, headache, retro-orbital pain, joint pain, myalgia, nausea and vomiting were more common in adult patients[8]. This study was undertaken to evaluate clinical profile and outcome of adult admitted with DHF/Dengue Shock Syndrome (DSS), dengue like illnesses amongst the adult admitted ii ABG Hospital Delhi from 2017.
References
- Dengue/dengue haemorrhagic fever. Weekly Epidemiological Report 75. 2000;24:193-200.
- Cho-Min-Naing. Assessment of dengue hemorrhagic fever in Myanmar. Southeast Asian J Trop Med and Pub Hlth. 2000; 31(4):636-41.
- Dengue/DHF: Trend of Dengue case and CFR in SEAR Countries. India. Available at: searo.who.int/en/Section10/Section332/Section2277.htm. Access date: July 2007.
- Dhooria G.S., Bhat D., Bains H.S. Clinical Profile and Outcome in Children of Dengue Hemorrhagic Fever in North India.Original Article Iran J Pediatrics Sep 2008; Vol 18 (No. 3), Pp:222-228.
- Kabra S.K. ,Verma I.C. ,Arora N.K. ,Jain Y., & KaIra V. Dengue haemorrhagic fever in children in Delhi. Bulletin of the World Health Organization, 70 (1): 105-108 (1992)
- Riaz M.M.,Mumtaz K.,Khan M.S.,Patel J.,Tariq M., Hilal H.,Siddiqui S.A.,Shezad F. Outbreak of Dengue Fever in Karachi 2006: a clinical perspective. J Pak Med Assoc. 2009;59(6): p339-344.
- Thomas L, Brouste Y, Najioullah F, Hochedez P, Hatchuel Y, Moravie V, Kaidomar S, King JP, Besnier F, Abel S, Carmès S, Schmitt S, Brihier P, Meunier C, Cardoso T, Rosine J, Quenel P, Césaire R, Cabié A. Prospective and descriptive study of adult dengue cases in an emergency department, in Martinique.Available at http://www.ncbi.nlm.nih.gov/sites/entrez
- Kittigul L, Pitakarnjanakul P, Sujirarat D, et al. The differences of clinical manifestations and laboratory findings in children and adults with dengue virus infection. J Clin Virol. 2007; 39(2):76-81.
- Ratageri VH, Shepur TA, Wari PK, et al. Clinical profile and outcome of dengue fever cases. Indian J Pediatr. 2005;72(8): 705-6.
- Faridi MMA, Aggarwal A, Kumar M, et al. Clinical and biochemical profile of dengue haemorrhagic fever in children in Delhi. Trop Doct. 2008;38(1): 28-30.
- Aggarwal A, Chandra J, Aneja S, et al. An epidemic of dengue hemorrhagic fever and dengue shock syndorme in children in Delhi. Indian Pediatr. 1998;35(8):727- 32.
- Rachel D, Philip R, Philip AZ. A study of clinical profile of dengue fever in Kollam, Kerala, India. Dengue Bul. 2005;29:196- 202.
- Ahmed S, Arif F, Yahya Y, et al. Dengue fever outbreak in Karachi 2006 - a study of profile and outcome of children under 15 years of age. J Pak Med Assoc. 2008; 58(1): 4-8.
- Peters CJ. Infections caused by arthropod- and rodent-borne viruses. In: Braunwald E, Fauci AS, Kasper DL, et al (eds). Harrison's Principles of Internal Medicine. 15th ed. New York: McGraw Hill. 2001: Pp:1152-66.
- Dengue haemorrhagic fever: diagnosis, treatment, prevention and control, 2nd ed. Geneva, Switzerland, World Health Organization, 1997.
- Kamath SR, Ranjit S. Clinical features, complications and atypical manifestations of children with severe forms of dengue hemorrhagic fever in South India. Indian J Pediatr. 2006;73(10):889-95
- Garacia-Rivera EJ, Rigan-Perez JG. Encephalitis and dengue. Lancet 2002; 360 (9328):261.
- Kankirawatana P, Chokephaibulkit K, Puthavathana P, et al. Dengue infections presenting with central nervous system manifestations. J Child Neurol. 2000;15(8): 544-7.
- Cam BV, Fonsmark L, Hue NB, et al. Prospective case-control study of encephalopathy in children with dengue hemorrhagic fever. Am J Trop Med Hyg. 2001;65(6):848-51.
- Thisyakorn U, Thisyakorn C, Limpitikul W, et al. Dengue infection with central nervous system manifestations. Southeast Asian J Trop Med Publ Health. 1999;30(3):504-6.
- Pancharoens C, Thusyakorn U. Neurological manifestations in dengue patients. Southeast Asian J Trop Med Publ Health. 2001;32(2):341-5.
- Cam BV, Fonsmark L, Hue NB, et al. Prospective case-control study of encephalopathy in children with dengue hemorrhagic fever. Am J Trop Med Hyg. 2001;65(6):848- 51.
- Malavige GN, Ranatunga PK, Jayaratne SD, et al. Dengue viral infections as a cause of encephalopathy. Indian J Med Microbiol. 2007;25(2):143-5.
Corresponding Author
Dr Shivam Yadav
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