Abstract
Background: Dengue fever is a hyper endemic viral infection in South-East Asia. We report some relatively rare cases of ocular complications of dengue fever.
Objective: To study the ocular manifestations of dengue fever.
Materials and Methods: The study was conducted among 532 patients diagnosed with dengue fever from May-June 2016 in a rural tertiary care hospital in Kerala, India. These patients were subjected to detailed ocular examination.
Result: A total of 8 patients (1.5%) were diagnosed to have ocular complications of dengue fever which comprised of anterior segment complications, posterior segment complications and transient changes in refraction.
Conclusion: The proportion of patients with ocular complications of dengue fever is very low in our study. However the ocular complications can range from subconjunctival haemorrhage, transient changes in refraction to severe posterior segment complications like neuroretinitis, choroiditis and macular oedema. Our study reveals transient myopia as a possible ocular manifestation in dengue fever which is not documented in other studies. This low proportion of ocular complications as reflected in this study may be due to better awareness about dengue fever in a very literate state like Kerala, better access to health care, early detection and timely medical intervention.
Keywords: Dengue fever, ocular manifestations, neuroretinities, macular oedema.
References
- World Health Organization. Dengue and Severe Dengue. Available at: http://www. fever – fact sheetwho.int/mediacentre-/factsheets/fs117/ en/ (last accessed on November 4, 2012).WHO. Dengue and dengue hemorrhagic, 2009 ;
- Sujatha R, Nousheen S, Nazlin A, Prakash S. Ocular manifestations of dengue fever. Int J Med Sci Public Health 2015;4:690-693
- Hussain I, Afzal F, Shabbir A, Adil A, Zahid A, Tayyib M. Ophthalmic manifestation of dengue fever. Ophthalmology Update 2012;10: 93-6.
- Nainiwal S, Garg SP, Prakash G, Nainiwal N. Bilateral vitreous haemorrhage associated with dengue fever. Eye (Lond) 2005;19:1012-3.
- Cruz-Villegas V, Berrocal AM, Davis JL. Bilateral choroidal effusions associated with dengue fever. Retina 2003;23: 576-8.
- Chlebicki MP, Ang B, Barkham T, Lande A. Retinal haemorrhages in 4 patients with dengue fever. Emerg Infect Dis 2005;11: 770-2.
- Siqueira RC, Vitral NP, Campos WR, Orefice F, de MoraesFigueiredo LT. Ocular manifestations in dengue fever. OculImmunolInflamm2004;12: 323-7.
- Lim WK, Mathur R, Koh A, Yeoh R, Chee SP. Ocular manifestations of dengue fever. Ophthalmology 2004;111: 2057-64.
- Sanjay s,AuEongKG.Bilateral vitreous haemorrhage associated with dengue fever.Eye(Lond).2007 Jan;21(1):144-5.
- De Amorim Garcia CA, Gomes AH, de Oliveria AG. Bilateral stellar neuroretinitis in a patient with dengue fever. Eye (Lond). 2006 Dec;20(12):1382-3.
- Cruz-Villegas V, BERROCALam, DavisI L. Bilateralchoroidal effusions associated with dengue fever.Retina.2003 Aug;23 (4):576-8.
- Pierre Filho Pde T, Carvalho Filho JP, Pierre ET. Bilateral acute angle closure glaucoma in a patient with dengue fever: case report. Arq Bras oftalmol.2008 Mar-Apr;71(2):265-8.
- Donnio A, Bral L ,Olindo S, Cabie A, Merle H. [Dengue,a new etiology in oculomotor paralysis.]Can J Ophthalmol. 2010Apr;45(2):183-4.doi10.1139/i09-207.
- Sanjay S, Wagle AM, Au Eong KG. Dengue optic neuropathy. ophthalmology. 2009 Jan;116(1):170.Author reply 170.Doi:10.1016/j.ophtha.2008.08.015.
- Niwanitkit V. Opsoclonus myoclonus ataxia associated with dengue. Parkinson-ismrel at disord.2015 feb;21(2):159. doi:10.1016/j.parkreldis.2014.11.008.
- Tan AH, Linn K, Sam IC, Tan CT, Lim SY. Opsoclonus myoclonus associated with dengue virus disease. Parkinsonismrel at disord.2015 feb;21(2):160-1.doi:10.1016/j.parkreldis.2014.11.009
- Wen KH, Sheu MM, Chung CB, Wang HZ, Chen CW. The ocular fundus findings in dengue fever. Gaoxiong Yi Xue Za Zhi1989;5: 24-30.
Corresponding Author
Sumitha Mary Jacob
Assistant Professor, Department of Ophthalmology
MOSC Medical College, Kolenchery, Kerala India