Abstract
Background: India contributes to more than 60% of leprosy case burden in the world.
Objective: To study the clinical profile of leprosy cases who attended the Dermatology outpatient department of a tertiary care unit during a period of one year, to document the diagnostic delay in individual case and to determine the role of rehabilitation age, sex and initial symptom as risk factors for diagnostic delay by analysing data from previous case records.
Methods: Retrospective study
Sample-Size-53 patients with diagnosed leprosey
Results: Among the 53 leprosy patients male to female ratio was 1.8:1. A diagnostic delay of more than one year was noted in 18 patients (34%). Age, sex and initial symptom were not found to be statistically significant risk factors for diagnostic delay.
Conclusion: Diagnostic delay of more than one year in one third of cases highlights the need to increase the efficacy of existing system to detect disease early.
Limitations: Small sample size and retrospective study.
Keywords: Leprosy, Diagnostic delay, Retrospective study.
References
- Pannikar V. Enhansed Global Strategy for Further Reducing the Disease Burden Due to Leprosy: 2011-2015. Lepr Rev 2009;80:353-4.
- Patro BK, Madhanraj K, Singh A. Is leprosy 'Elimination' a conceptual illusion?. Indian J Dermatol Venereol Leprol 2011;77:549-51.
- WHO expert committee on leprosy. Eighth report. Technical report series 968. World Health Organisation, Geneva, 2010.
- Lockwood DNJ, Nicholls P, Smith WCS et al. Comparing the clinical and histological diagnosis of leprosy and leprosy reactions in the INFIR cohort of Indian Patients with multibacillary leprosy. PLoSNegl Trop Dis, 2012; 6: e1702.
- Sasidharanpillai S, ReenaMariyath OK, Riyaz N, Binitha MP, George B, Janardhanan AK, et al. Changing trends in leprosy among patients attending a tertiary care institution. Indian J Deramatol VenereolLeprol 2014; 80: 338-40.
- Shen J, Liu M, Zhou M, Wengzhong LI. Occurrence and management of leprosy reaction in China in 2005. Lepr Rev 2009; 80: 164–9.
- Stella M. Van Beers, Mohammad Hatta and Paul R. Klaster et al. Patient contact is the major determinant in incident leprosy implication for future contact. Int J Lepr Other Mycobact Dis 1999; 67:119-28.
- Nascimento OJM. Leprosy neuropathy: clinical presentations. ArqNeuropsiquiatr 2013; 71: 661-6.
- Lema T., Woldeamanuel Y., Asrat D., Hunegnaw M., Baraki A., Kebede Y. The pattern of bacterial isolates and drug sensitivities of infected ulcers in patients with leprosy in ALERT, Kuyera and Gambo hospitals, Ethiopia. Lepr Rev. 2012; 83(1):40–51.
- Sarkar R, Pradhan S. Leprosy and women. Int J Women’s Dermatol 2016; 2: 117-21.
- Scollard DM, Smith T, Bhoopat L, Theetranont C, Rangdaeng S, Morens DM. Epidemiologic characteristics of lepra reactions. Int J Leprosy 1994; 62: 559-67.
- Peters E.S., Eshiet A.L. Male–female (sex) differences in leprosy patients in south eastern Nigeria: females present late for diagnosis and treatment and have higher rates of deformity. Lepr Rev. 2002;73: 262–67.
Corresponding Author
Dr Swapna Dominic
Assistant Professor, Dept of Dermatology, Govt. Medical College Kozhikode, Kerala, India
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