Abstract
Wilson’s disease is an inherited autosomal recessive disorder of copper metabolism. As a consequence copper accumulates in liver, brain, kidney and red blood cells. Patients may develop chronic liver disease, hemolytic anaemia and neurological symptoms. Hepatic involvement may interfere with metabolism of various anaesthetic drugs. Anaesthesia for deformity correction of scoliosis itself is challenging and associated with various complications. Very few cases has been reported of anaesthetic management in patients with wilson’s disease associated with scoliosis.
Keywords: Wilson’s disease, scoliosis, General Anaesthesia.
References
- De Souza Hobaika AB. Anesthesia for a patient with Wilson's disease – A case report. Middle East J Anaesthesiol 2008;19:905-8.
- Markiewicz-Kijewska M, Szymczak M, Ismail H, Prokurat S, Teisseyre J, Socha P, et al.Liver transplantation for fulminant Wilson's disease in children. Ann Transplant 2008;13:28-31.
- Dikmen PY, Baybas S, Aydinlar EI, Kaymakoglu S, Onur E, Keskinbora K. A case of Wilson's disease with acute neuropsychiatric symptoms after general anesthesia. Archives of Neuropsychiatry. 2008;45(1):21–2.
- Maze M, Bass NM. Anesthesia and the hepatobiliary system. In: Miller RD, editor. Miller's Anesthesia. Philadelp-hia: Churchill Livingstone; 2000. pp. 1960–72.
- Athar M, Ahmed SM, Ali S, Doley K, Varshney A, Siddiqi MM. Levobupivacaine or ropivacaine: A randomised double blind controlled trial using equipotent doses in spinal anaesthesia. Rev Colomb Anestesiol 2016;44:97-104
- Tanaka K, Kamekura N,Teramoto T, Kimura Y, Fukushima K. Anaesthetic Management of a Patient with Wilson’s Disease. JDSA. 1999;27(3):326-31.
- Baykal M, Karapolat S. Anaesthetic Management of a Paediatric Patient with Wilsons Disease. J Clin Med Res. April 2010;2(2):99–101.
Corresponding Author
Vasudha Gupta
Department of Anaesthesia, AIIMS, New Delhi
Mobile No: 9781406528, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v6i4.180
