Abstract
The OGTT is an important tool for the diagnosis of Diabetes mellitus. Patients and clinical staff need to be aware of the potential for misdiagnosis when standard instructions regarding patient conduct before and during the test are not followed. Source of information regarding the protocol is an important aspect considering the complexity of patient preparation involved in Oral glucose tolerance test.
Keywords: Oral glucose tolerance test (OGTT), preanalytical errors in OGTT, patient preparation, OGTT protocol.
References
- American Diabetes Association. Classification and diagnosis of diabetes. Sec. In Standards of Medical Care in Diabetes2017. Diabetes Care 2017;40(Suppl. 1):S11–S24
- Lippi G, Chance JJ, Church S, Dazzi P, Fontana R, Giavarina D, et al. Preanalytical quality improvement: from dream to reality. Clin Chem Lab Med [Internet]. 2011 Jan 1 [cited 2017 Feb 11];49(7). Available from: http://www.degruyter.com/view/j/cclm.2011.49.issue-7/cclm.2011.600/cclm.2011.600.xml
- Association AD. Standardization of the Oral Glucose Tolerance Test: Report of the Committee on Statistics of the American Diabetes Association, June 14, 1968. Diabetes. 1969 May 1;18(5):299–310.
- Randle, P.J., Garland, P.B., Hales, C.N. &Newsholme, E.A. (1963) The glucose fatty acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetic mellitus. Lancet, I, 785 789.
- Federici, M., Mosca, A., Testa, R., et al. (2011). National survey on the execution of the oral glucose tolerance test (OGTT) in a representative cohort of Italian laboratories. Clinical Chemistry and Laboratory Medicine (CCLM), 44(5), pp. 568-573. Retrieved 28 Mar. 2018, from doi:10.1515/CCLM.2006.100
- Bankovic Radovanovic P, Kocijancic M. How well are pregnant women in Croatia informed about the oral glucose tolerance test? Biochem Medica. 2015;25(2):230–6.
- pdf [Internet]. [cited 2017 Aug 14]. Available from:https://ec.europa.eu/health//sites/health/files/systems_performance_assessment/docs/eurobaro_patient_involvement_2012_en.pdf
- The Royal Australian College of General Practitioners. Standards for general practices. South Melbourne: The RACGP, 2010.
- Kljakovic M. Patients and tests - a study into patient understanding of blood tests ordered by their doctor. Aust Fam Physician. 2012 Apr;41(4):241–3.
- Narayanan S. The preanalytic phase. An important component of laboratory medicine. Am J Clin Pathol. 2000 Mar;113(3):429–52.
- Ryan J, Siriwardhana D, Vasikaran SD. An audit of oral glucose tolerance tests at a large teaching hospital: indications, outcomes and confounding factors. Ann Clin Biochem. 2009 Sep 1;46(5):390–3.
- Taylor, S. I. Diabetes mellitus. In: C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle(Eds), The Metabolic and Molecular Bases of Inherited Disease, 7th ed. New York:McGrawHill,1995, pp. 843–896.devlin
- Wilkerson, H. L. C, Hyman, H., Kaufman, M., Mc- Cuistion, A. C, and Francis, J. O.: Diagnostic evaluation of oral glucose tolerance tests in nondiabetic subjects after various levels of carbohydrate intake. New Eng. J. Med. 262: 1047-53, i960.
- Conn, J.W. (1940) Interpretation of the glucose tolerance test. The necessity of a standard preparatory diet. Am. J. Med. Sci., 199, 555-564.
- Overview of Indian Diet | Cadi [Internet]. [cited 2017 Sep 4]. Available from:http://www.cadiresearch.org/topic/diet-indian/indian-diet-overview
- Dietary guidelines forn in website.pdf [Internet]. [cited 2017 Sep 4]. Available from:http://ninindia.org/dietaryguidelinesforninwebsite.pdf
- Shridhar K, Dhillon PK, Bowen L, Kinra S, Bharathi AV, Prabhakaran D, et al. Nutritional profile of Indian vegetarian diets – the Indian Migration Study (IMS). Nutr J.2014 Jun 4;13:55.
Corresponding Author
Harini Challapalli
Department of Biochemistry,
St. John’s Medical College, Bangalore, India