Title: Paroxysmal Cold Hemoglobinuria: A Rare Case Presentation
Authors: Dr Shreya Sinha, Dr Ankit Saxena, M.D. (Medicine)
DOI: https://dx.doi.org/10.18535/jmscr/v6i4.102
Abstract
Background
Paroxysmal cold hemoglobinuria (PCH) is a rare cause of acquired autoimmune hemolytic anaemia (AIHA) commonly seen in children post viral infections caused by complement dependent cold acting autoantibodies that produce intravascular hemolysis and hemoglobinuria in vivo and gives rise to Donath-Landteiner (D-L)reaction in vitro.
