Abstract
Background: Thyroid disorders are among the commonest endocrine disorders in India as well as across the world. It has been estimated that about 42 million people in India suffer from thyroid diseases. The prevalence and pattern of thyroid disorders depends on sex, age, ethnic and geographical factors and especially on iodine intake. Thyroid disease is being increasingly diagnosed with greater awareness and is one of the chronic non communicable disease affecting women more, though male population is not spared of the ailment. Studies from various research workers discuss the proportion of thyroid disorder among Indian states like Delhi, Mumbai, Kolkata, Bangalore, Chennai, Goa etc but there is paucity of data from the rural areas. The present study was conducted to find out the prevalence of thyroid disorders among the people of Rohtas district of Bihar.
Material and Methods: This is the observational, retrospective study conducted in department of Biochemistry Narayan Medical College & Hospital, Sasaram, Bihar. In total, 2178 patients visiting to hospital and suspecting of thyroid disorders were screened for thyroid function. Thyrotrophin (TSH), triiodothyronine (T3), and tetraiodothyronine (T4) in human serum were quantitatively estimated. Statistical analysis was performed by SPSS version 20 software.
Results: Of the 2178 total subjects in the age range 1 to 80 years, 31.0% had thyroid dysfunction and 69.0% had euthyroidism; 17.0% had subclinical hypothyroidism, 8.3% had overt hypothyroidism; 4.1% had overt hyperthyroidism while 1.6% had subclinical hyperthyroidism.
Conclusion: Our study suggests that the prevalence of thyroid disorders in our study population is high with female preponderance and subclinical hypothyroidism is the commonest abnormality, followed by overt hypothyroidism, overt hyperthyroidism and subclinical hyperthyroidism. The study is the first effort from Bihar towards the proportion of thyroid disorder. Being iodine deficient area as well, proper awareness is required for the control of disease so that its prevention and associated diseases can be minimized.
Keywords: Hypothyroidism, Hyperthyroidism, Subclinical Hypothyroidism, Subclinical Hyperthyroidism.
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Corresponding Author
Sudhanshu Shekhar
Assistant Professor, Department of Biochemistry,
Narayan Medical College & Hospital, Sasaram, Bihar
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v6i4.97
