Abstract
Introduction: Type 2 diabetes has recently escalated in all age groups and is now being seen in younger age groups, including adolescents, especially in high risk populations. Anaemia is one of the common finding in diabetes, particularly in patients with albuminuria or renal impairment. Recent studies have shown that at least 1 in 5 out patients with type 1 or type 2 diabetes in tertiary clinics have anaemia, in which it constitutes a significant additional burden.
Material & Methods: Study was conducted in the Postgraduate department of Pathology and department of Medicine, Government Medical College and associated hospitals, Jammu. It was prospective extending over a period of one year from 1st November 2011 to 31st October 2012. Observations comprised of: History, General physical examination, Systemic examination, haematological Investigations Biochemistry including urine examination.
Results: The main study was done on 87 patients. Out of 87 cases 41(47.12%) patients showed microcytic blood picture, 24(27.58%) patients showed dimorphic blood picture, 19(21.83%) patients showed predominantly macrocytic blood picture and 3(3.44%) patients showed normocytic normochromic blood picture. The prevalence of anaemia among diabetics in our study came out to be 58%.
Conclusion: Anaemia is an important cause of physical and mental impairments in diabetic patients including malaise, fatigue, weakness and other symptoms. Although anaemia represents an unwelcome additional burden in patients with diabetes. Fortunately, anaemia can be treated, and improved quality of life can be achieved.
Keywords: Anaemia; Diabetes; Iron deficiency; Albuminuria; Megaloblastic anaemia.
References
- WHO Technical Report Series No 916 (TRS-916): 2003.
- Stevens PE,O'Donoghue DJ, Lameire NR. Anaemia in patients with diabetes: unrecognised, undetected and untreated? Curr Med Res Opin. 2003; 19(5):395-401.
- Merlin Thomas C. High prevalence of anaemia in Diabetes linked to erythropoietin deficiency, 2006: vol. 26, no4; 275-282.
- David C Holland, Miu Lam. Predictors of hospitalization and death among pre-dialysis patients: Nephrol Dial Transplant, 2000: 15; 650-658.
- David MD, Fisher MR et al. Risk factor for high risk proliferative diabetic retinopathy and severe visual loss: Invest Ophthalmol Vis Sci, 1998 Feb: 39(2); 233-252.
- Jones SC,Smith D, Nag SPrevalence and nature of anaemia in a prospective, population-based sample of people with diabetes:Teesside anaemia in diabetes (TAD) study.Diabet Med. 2010 Jun; 27(6):655-9.
- Bosman DR,Winkler AS, Marsden JT et al Anaemia with erythropoietin deficiency occurs early in diabetic nephropathy. Diabetes Care. 2001 Mar; 24(3):495-9.
- David R Thomas. Anaemia in Diabetic patients: Clinics in Geriatric Medicine, Aug 2008: Vol. 24, Issue 3, 529-540.
- P Malhotra, Savita Kumari et al. Prevalence of Anaemia in Adult Rural population of North India: J. Assoc Physicians India, Jan 2004: 52; 18-19.
- Stevens PE,O'Donoghue DJ, Lameire NR. Anaemia in patients with diabetes: unrecognised, undetected and untreated? Curr Med Res Opin. 2003; 19(5):395-401.
- Bonakdaran S,Gharebaghi M, Vahedian M. Prevalence of anaemia in type 2 diabetes and role of renal involvement. Saudi J Kidney Dis Transpl. 2011 Mar; 22(2):286-90.
- Ahmed AT,Go AS, Warton EM et al Ethnic differences in anaemia among patients with diabetes mellitus: the Diabetes Study of Northern California Am J Hematol. 2010 Jan; 85(1):57-61.
- Dimković N;Studijske Grupe. Anaemia in patients with diabetes mellitus.Med Pregl. 2007 May-Jun;60(5-6):225-30.
- Thomas MC,MacIsaac RJ, Tsalamandris C et al Unrecognized anaemia in patients with diabetes: a cross-sectional survey. Diabetes Care. 2003 Apr; 26(4):1164-9.
- Waggiallah H,Alzohairy M. The effect of oxidative stress on human red cells glutathione peroxidase, glutathione reductase level, and prevalence of anaemia among diabetics. N Am J Med Sci. 2011 Jul; 3 (7):344-7.
- Brill JR,Baumgardner DJ. Normocytic anaemia. Am Fam Physician. 2000 Nov 15;62(10):2255-64.
- Kovács F,Szakál I, Révész K, Lévai A, Dobos A. Anaemia and iron metabolism in patients with type-2 diabetes mellitus. Orv Hetil. 2006 Feb 26; 147(8):345-9.
- McCance DR, Hanson RL, et al. Comparison of tests for glycated haemoglobin and fasting and two hour plasma glucose concentrations as diagnostic methods for diabetes. BMJ 1994; 308: 132-38.
- Jones SC,Smith D, Nag SPrevalence and nature of anaemia in a prospective, population-based sample of people with diabetes: Teesside anaemia in diabetes (TAD) study.Diabet Med. 2010 Jun; 27(6):655-9.
- Kengne AP, Czernichow S, Hamer M, et al anaemia, haemoglobin level and cause-specific mortality in people with and without diabetes PLoS One. 2012;7(8):e41875. Epub 2012 Aug 2.
Corresponding Author
Tazeen Jeelani
Lecturer Dept of Pathology Govt Medical College Srinagar Jammu and Kashmir India 190010
Phone: +919070129836, +919018267086, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.