Abstract

Background: Bone marrow aspiration is important investigation of haematological disorders not being clearly diagnosed on peripheral blood examination.

Objective: The present study was done to find out prevalence of etiological diagnosis in hypercellular and hypocellular bone marrow aspirates.

Material and Methods: The present study was conducted in the Department of Pathology, M.G.M. Medical College Indore, from January 2017 to February 2018. Total 38 cases were studied. The diagnosis in all the cases were made on Field stained and Leishman stained slides of bone marrow aspirates.

Results: Among the 38 cases, 26.3% shows Megaloblastic anemia, 7.9% shows Aplastic Anemia, 15.7% shows Hypoplastic Bone marrow, 2.6% shows Erythroid hyperplasia, 5.3% shows Immune Thrombocytopenic Purpura, 7.9% shows Myeloproliferative disorder, 5.3% shows Myelodysplastic syndrome, 5.3% shows Acute Lymphoblastic Leukemia, 13.2% shows Acute Myeloid Leukemia, 2.6% shows Chronic myeloid leukemia, 5.3% shows NHL spillage, 2.6% shows Metastatic deposits. Among all cases 20 were males and 18 were females.

Conclusion: Bone marrow aspiration is easy and cheap investigation in evaluation of haematological and non-haematological disorders of bone marrow. Majority of bone marrow aspirates were hypercellular, among which common finds were Megaloblastic anemia and acute leukemia.

Keywords: Bone marrow aspiration, Megaloblastic anemia, Acute leukemia.