Title: Comparative Study of Analgesia Produced by Thoracic Epidural and Intravenous Opioid in Cases of Multiple Rib Fracture
Authors: Dr Pankaj Kumar Omar, Dr Shipra Surin, Dr Anikta Borkar
DOI: https://dx.doi.org/10.18535/jmscr/v6i2.153
Abstract
Introduction
Thoracic trauma is a significant cause of morbidity and mortality in our society. It ranks second only to head injury as a cause of traumatic death in USA. One of every four death resulting from trauma is attributable to a thoracic etiology. 1
Multiple rib fracture causes severe pain and is the most common of all chest injuries and is indentified in 10% of patients after trauma.3A The overall incidence may be higher as not all rib fractures are seen on chest x-ray or otherwise detected.
Rib fracture is a marker of severe bodily and solid organ injury. Rib fractures are associated with concomitant thoracic, head, extimity, abdominal and blunt cardiac injury2-5 Patients are at increased risk of multiple complications and have poor prognosis. Multiple rib fractures cause severe pain which may be more debilitating and harmful than the injury itself.1 Multiple rib fractures contribute significantly to the morbidity and mortality of the injured patients with the elderly 1 and patients with poor respiratory reserves being most vulnerable.
References
- Trunkey DD. Trauma. Scientific American 1983; 249: 28–35. [PubMed]
- Ziegler DW, Agarwal NN . The morbidity and mortality of rib fractures. J Trauma 1994;37:975–9.
- Flagel BT, Luchette FA, Reed RL, Esposito TJ, Davis KA, Santaniello JM, Gamelli RL. Half-a-dozen ribs: the breakpoint for mortality. Surgery 2005;138:717–23; discussion 723–5.
- Cha±an BC, Herbert B, Rodil M, Salotto J,Stovall RT, Biffl W, Johnson J, Burlew CC, Barn ett C, Fox C, et al. RibScore: a novel radiographic score based on fracture pattern that predicts pneumonia, respiratory failure, and tracheostomy. J Trauma Acute Care Surg 2016;80:95–101.
- Bulger EM, Arneson MA, Mock CN, Jurkovich GJ. Rib fractures in the elderly. J Trauma 2000;48:1040–6; discussion 1046–7.
- Mackersie RC, Shackford SR, Hoyt DB, et al. Continuous epidural fentanyl analgesia: ventilatory function improvement with routine use in treatment of blunt chest injury. J Trauma 1987; 27: 1207. [PubMed]
- Wimpy R, Hubbard L, McCormick M, Fortune JB. The treatment of patients with multiple rib fractures using continuous thoracic epidural narcotic infusions. Reg Anesth 1987; 12: 48. [PubMed]
- Jones MT, Gillham B. Factors involved in the regulation of adrenocorticotropic hormone/beta-lipotropic hormone. Physiol Rev 1988; 68: 743–750. [PubMed]
- Cicala RS, Voeller GR, Fox T, et al. Epidural analgesia in thoracic trauma: effects of lumbar morphine and thoracic bupivacaine on pulmonary function. Crit Care Med 1990; 18: 229. [PubMed]
- Luchette FA, Radfshar MR, Kaiser R, et al. Prospective evaluation of epidural versus intrapleural catheters for analgesia in chest wall trauma. J Trauma 1994; 36: 865–870. [PubMed]
- Pape HC, Remmers D, Rice J, Ebisch M, Krettek C, Tscherne H. Appraisal of early evaluation of blunt chest trauma: develo±ent of a standardized scoring system for initial clinical decision making. J Trauma 2000;49:496–504.
- Simon BJ, Cushman J, Barraco R, et al. Pain management guidelines for blunt thoracic trauma. J Trauma Inj Infect Crit Care 2005; 59:1256–67.
- Karmakar MK, Ho AM-HM. Acute pain management of patients with multiple fractured ribs. J Trauma-Inj Infect. 2003;54: 615–25.
- Sırmalı M. A comprehensive analysis of traumatic rib fractures: morbidity, mortality and management. Eur J Cardiothorac Surg 2003;24:133–8.
- Fulda GJ, Giberson F, Fagraeus L. A Prospective randomized trial of nebulized morphine compared with patient-controlled analgesia morphine in the management of acute thoracic pain. J Trauma-Inj Infect. 2005;59:382–9.
- Haenel JB, Moore FA, Moore EE, et al. Extrapleural bupivacaine for amelioration of multiple rib fracture pain. J Trauma 1995;38:22–7.
- Truitt MS, Murry J, Amos J, et al. Continuous intercostal nerve blockade for rib fractures: ready for primetime? J Trauma Inj Infect Crit Care 2011;71:1548–52.
- Karmakar MK. Continuous thoracic paravertebral infusion of bupivacaine for pain management in patients with multiple fractured ribs. Chest 2003;123:424–31.
- Flagel BT, Luchette FA, Reed RL, et al. Half-a-dozen ribs: the breakpoint for mortality. Surgery 2005;138:717–25.
- Worthley LIG. Thoracic epidural in the management of chest trauma: a study of 161 cases. Intensive Care Med 1985;11:312–5.
- Kieninger AN, Bair HA, Bendick PJ, et al. Epidural versus intravenous pain control in elderly patients with rib fractures. Am J Surg 2005;189:327–30.
- Bulger EM, Edwards T, Klotz P, et al. Epidural analgesia improves outcome after multiple rib fractures. Surgery 2004;136:426–30.
- O’Kelly E, Garry B. Continuous pain relief for multiple fractured ribs. Br J Anaesth. 1981;53:989–991.
- Mackersie RC, Karagianes TG, Hoyt DB, Davis JW. Prospective evaluation of epidural and intravenous administration of fentanyl for pain control and restoration of ventilatory function following multiple rib fractures. J Trauma. 1991;31:443–449.
- Haenel JB, Moore FA, Moore EE, Sauaia A, Read RA, Burch JM. Extrapleural bupivacaine for amelioration of multiple rib fracture pain. J Trauma. 1995;38:22–27.
- Moon MR, Luchette FA, Gibson SW, et al. Prospective, randomized comparison of epidural versus parenteral opioid analgesia in thoracic trauma. Ann Surg. 1999;229:684–691.
- Linton DM, Potgieter PD. Conservative management of blunt chest trauma. S Afr Med J. 1982;61:917–919.
- Shackford SR, Virgilio RW, Peters RM. Selective use of ventilator therapy in flail chest injury. J Thorac Cardiovasc Surg. 1981; 81:194–201.
- Bulger EM, Edward T, Klotz P, et al. Epidural analgesia improves outcome after multiple rib fractures. Surgery 2004; 136: 426-430.
- Topcu I, Ekici Z, Sakarya M. [Comparison of clinical effectiveness of thoracic, epidural and intravenous patient-controlled analgesia for the treatment of rib fracture pain in intensive care unit]. Ulus Travma Acil Cerrahi Derg 2007; 13: 205-210.
- Ulman DA, Fortune JB, Greenhouse BB, et al. The treatment of patients with multiple rib fractures using continuous thoracic epidural narcotic infusion. Reg Anesth 1989; 14: 43-47.
- Wu CL, Jani ND, Perkins FM, et al. Thoracic epidural analgesia versus intravenous patient-controlled analgesia for the treatment of rib fracture pain after motor vehicle crash. J Trauma 1999; 47: 564-567.
- Moon MR, Luchette FA, Gibson SW, et al. Prospective, randomized comparison of epidural versus parenteral opioid analgesia thoracic trauma. Ann Surg 1999; 299: 684-691.
- Stawicki SP, Grossman MD. Hoey BA. et al. rib fractures in the elderly: a marker of injury severity. J Am Geriatr Soc 2004; 52: 805-808.
- Mackersie RC, Shackford SR, Hoyt DB, et al. Continuous epidural fentanyl analgesia: ventilatory function improvement with routine use in treatment of blunt chest injury. J Trauma 1987; 27: 1207-1212.
- Shulman M, Sandler AN, Bradley JW, et al. Postthoracostomy pain and pulmonary function following epidural and systematic morphine. Anesthisiology 1984; 61: 569-575.
- Zwarts SJ, Hasenbos MA, Gielen MJ, et al. The effect of continuous epidural analgesia with sufentanil and bupivacaine during and after thoracic surgery on the plasma cortsol concentration and pain relief. Reg Anesth 1989; 14: 183-188.
- Bulger EM, Edwards T, Klotz P, et al. Epidural analgesia improves outcome after multiple rib fractures. Surgery. 2004; 136: 426-430.
- Karmakar MK, Ho AM. Acute pain management of patients with multiple fractured ribs. Journal of Trauma. 2003; 54(3): 615-25.
- Kieninger AN, Bair HA, Bendick PJ, Howells GA. Epidural versus intravenous pain control in elderly patients with rib fractures. Am J Sur. 2005; 189: 327-30.
- Wu CL, Jani ND, Perkins FM, et al. Thoracic epidural analgesia versus intravenous patient-controlled analgesia for the treatment of rib fracture pain after motor vehicle crash. J Trauma. 1999; 47: 564-7.
- Winser DH. A stepwise logistic regression analysis of factors affecting morbidity and mortality after thoracic trauma: effect of epidural analgesia. J Trauma. 1990; 30: 799-804.
- Liu S, Carpenter RL, Neal JM. Epidural anesthesia and analgesia. Their role in postoperative outcome. Anesthesiolgy 1995; 82: 1474-1506.
- Cicala RS, Voellar GR, Fox T, et al. Epidural analgesia in thoracic trauma: effects of lumbar morphine and thoracic bupivacaine on pulmonary function. Crit Care Med 1990; 18: 229-231.
- Pansard JL, Mankikian B, Bertrand M, et al. Effects of thoracic extradural block on diaphragmatic electrical activity and contractility after upper abdominal surgery. Anesthesiology 1993; 78: 63-71.
- Fratacci MD, Kimball WR, Wain JC, et al. Diaphragmatic shortening after thoracic surgery in humans. Effects of mechanical ventilation and thoracic epidural anesthesia. Anesthisiology 1993; 79: 654-665.
- Kavanagh BP, Katz J, Sandler AN. Pai n control after thoracic A review of current tec hniques. Anesthesiol ogy 19 94;81:73 7-759.
- Wiebalck A, Brodner G, Van Aken H. The effects of adding sufentanil to bupivacaine for postoperati ve patient-controlle d epidural analgesia. Anesth Analg 1997;85:124-129.
- Hansdottir V, Bake B, Nordberg G. The analgesic efficacy and adverse effects of continuous epidural sufentanil and bupivacaine infusion after thoracotomy. Anesth Analg 1996;83:394-400.
- Badner NH, Bhandari R, Komar WE. Bupivacaine 0.125% improves continuous postoperative epidur al fentanyl analgesia after abdominal or thoracic surger y. Can J Anaesth 1994;41:387-392
- Ansantila R, Rosenberg PH, Scheinin B. Comparison of different methods of postoperative analgesia after thoracostomy. Acta Anaesthesiol Scand 1986; 30: 421-425.
- Bulger EM, Edwards T, Klotz P, et al. Epidural analgesia improves outcome after multiple rib fractures. Surgery 2004;136:426–30.
- Mohta M, Verma P, Saxena AK, et al. Prospective, randomized comparison of continuous thoracic epidural and thoracic paravertebral infusion in patients with unilateral multiple fractured ribs–a pilot study. J Trauma 2009;66:1096–101.