Abstract
Subclinical thyroid disease is defined biochemically by an abnormal thyrotropin (TSH) level and normal serum –free thyroxine level. The prevalence of this condition varies according to the reference range for TSH and geographic or demographic factors. Whereas iodine rich diet is necessary for proper thyroid gland function substantial numbers of patients have risk of SCH getting converted into primary hypothyroidism and subclinical hypothyroidism is associated with serious complications. The iodine intake is inversely correlated with thyroid function; deficient iodine intake is related with hyperthyroid status while excessive or sufficient intake of iodine is associated with hypothyroidism.
This study was conducted on 500 people attending the OPD in the Department of Medicine in collaboration with Department of Medicine, at Government Medical College Jammu from January 2017-March 2017. Out of the total, only 102 (20.4%) cases had SCH, with females comprising the majority (79.4%). Patients with TSH >4.3 mIU/ml and T3 and T4 in normal reference range are considered suffering from subclinical hypothyroidism (SCH).
The result clearly reflects the incidence of SCH amongst the demography of the region showing prevalence amongst the elderly and women. Despite all these known facts women still continue to suffer. Subclinical hypothyroidism affects 3-15% of adult population. Its clinical and biochemical profile not well defined, especially in Indian scenario.
Keywords: Subclinical hypothyroidism, thyroid stimulating hormone, Iodine.
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Corresponding Author
Dr Ashima Badyal
214 Av Shastri Nagar, Jammu, J&K, India- 180004
DOI: https://dx.doi.org/10.18535/jmscr/v6i2.76
