Abstract

Background: Several studies have shown that excessive use of fluoride toothpaste can cause bone loss, kidney problems, decreased IQ and gastric disorders, especially in children. 

Objectives: This study aims to make preparations of excellent and stable toothpaste from the combination of coarse waste bromelain pineapple (Ananas comosus L. Merr var Quin) and papain rind of papaya (Carica papaya L) as well as to examine the effect as an anti-plaque toothpaste.

Methods: The toothpaste obtained was tested for 28 days regarding physical stability including pH, viscosity, foam height, homogenous, color, smell, and taste. The effectiveness of the antiplaque dentifrice preparations was tested on 25 volunteers for seven days.

Results: The results showed that for the physical stability pH, viscosity, homogeneity, high foam, color, and smell meets the requirements and preparation do not irritate the skin. ANOVA statistical test (p <0.05) showed that there was a significant difference between the average deviation of plaque score group toothpaste containing a combination of bromelain and papain. But at  Posthoc Test, the  average difference of  toothpaste plaque score group showed no significant difference

Conclusions:  It can be concluded that the toothpaste containing a combination of bromelain and papain meet the requirements of the physical stability and affect the effectiveness of anti-plaque toothpaste with the most efficient combination is 4.25%:0.75%.

Keywords: Toothpaste, waste pineapple, bromelain, papain, Score Plaque.