Title: Gender Difference of Lipid Profile in a South Indian Population with Acute Coronary Syndrome - A Cross Sectional Study
Authors: Dr Jayachandran. R, Rajesh.V.R, Dr Lijo K Mathew
DOI: https://dx.doi.org/10.18535/jmscr/v6i1.147
Abstract
Background: Dyslipidemia is one of the most important modifiable and treatable risk factor for coronary heart disease (CHD). Gender difference in lipid profile of patient with acute coronary syndrome (ACS) is not studied before in south Indian population.
Objective: To evaluate co-gender variation of lipid profile in patients with ACS and to find out its association with other risk factors of ACS.
Methods: A cross sectional study conducted among 100 male and 100 female patients above the age 18 years and alive after 48 hrs admission, admitted with signs and symptoms of unstable angina (UA), non ST evaluation myocardial Infarction (NSTEMI) and ST Elevation Myocardial Infarction (STEMI) are selected.
Results: - incidence of Diabetes Mellitus (DM) in study was 31%. Diabetic patients had higher mean total cholesterol, higher mean LDL Cholesterol (LDL-C), lower mean HDL- Cholesterol (HDL-C) than patients without diabetes. Males had higher T-C while females had higher HDL-C and higher TG. Over weight and obese patients had higher TC, higher mean LDL-C and TG and lower mean HDL.
Conclusions
- Elevated TC, LDL-C and TG and a lower HDL-C is observed in the study group.
- Females had higher HDL-C and TG while males had Higher TC and LDL-C.
- Physical inactivity positive family history of ACS DM, HTN, Smoking and high BMI had a strong correlation with FLP.
Keywords: Coronary Heart Disease, Acute Coronary Syndrome, Myocardial Infarction, Cardiovascular Disease.
