Abstract
Malignant melanoma of the conjunctiva is a rare condition. It is managed by local excision with or without supplementary cryotherapy. Despite an adequate excision, local recurrences are not uncommon. Systematic metastases occur to lung, liver, skin, bone or the gastrointestinal tract (GIT). Metastasis to the genitourinary tract has rarely been reported. Simultaneous occurrence of conjunctival melanoma and transitional cell carcinoma of the urinary bladder, however, has never been reported. Our case report, to the best of our knowledge, presents this association, for the first time.
Keywords: Conjunctival Malignant Melanoma, Excision biopsy, Transitional cell carcinoma.
References
- Brownstein S. Malignant Melanoma of the Conjunctiva. Cancer Control 2004;11(5): 310-16.
- Seregard S. Conjunctival Melanoma. SurvOphthalmol 1998; 42:321-50.
- Jakobiec FA. Conjunctival Melanoma. Arch Ophthalmol 1980; 98:1378-84.
- Paridaens AD, Minassian DC, McCartney AC, et al. Prognostic factors in primary malignant melanoma of the conjunctiva: a clinicopathological study of 256 cases. Br J Ophthalmol 1994;78:252-59.
- Esmaeli B, Wang X, Youssef A, et al. Patterns of regional and distant metastasis in patients with conjunctival melanoma: Experience at a cancer center over four decades. Ophthalmology 2001;108:2101-05.
- Jakobiec FA, Rini FJ, Fraunfelder FT, et al. Cryotherapy for conjunctival primary acquired melanosis and malignant melanoma. Experience with 62 cases. Ophthalmology 1988;95:1058-70.
- Folberg R, Mc Lean IW, Zimmerman LE. Malignant melanoma of the conjunctiva. Hum Pathol 1985;16:136-43.
- Shields CL, Shields JA, Gunduz K, et al. Conjunctival melanoma: Risk factors for recurrence, exenteration, metastasis and death in 150 consecutive patients. Arch Ophthalmol 2000;118: 1497-1507.
- Stein BS, Kendall AR. Malignant melanoma of the genitourinary tract. J Urol 1984;132:859-68.
- Dasgupta T, Grabstald H: Melanoma of the genitourinary tract. J Urol 1965;93:607-14.
- Golstein HM, Kaminsky S, Wallace S, et al. Urographic manifestations of metastatic melanoma. Am J Roentgenol Radium TherNucl Med 1974;121:801-05.
- Amar AD: Metastatic melanoma of the bladder. J Urol 1964;92:198-200.
- Nair BCJ, Williams NC, Cui C, et al. Conjunctival Melanoma: Bladder and Upper Urinary Tract Metastases. Journal of Clinical Oncology 2011;29:216-9.
- Melichar B, Ryska A, Vesely P, et al. Triple malignancy in a patient with conjunctival melanoma. J FrOphthalmol 2008:31(2):4.
Corresponding Author
Dr (Col) Sandeep Shankar
Associate Professor, Department of Ophthalmology,
Armed Forces Medical College, Pune-411040, Maharashtra, India
Mobile: 9882829560, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v6i1.146
