Title: A Comparative Study of Dexmedetomidine versus Magnesium Sulphate as an Adjuvant to Ropivacaine in Bier’s Block in Upper Limb Surgery
Authors: Gill Rabia, Guliani Gurpreet
DOI: https://dx.doi.org/10.18535/jmscr/v6i1.136
Abstract
This prospective randomised double-blinded study was designed to compare the effects of adding dexmedetomidine and magnesium sulphate to ropivacaine during bier’s block. Fifty ASA I or II patients scheduled for upper limb surgery under bier’s block were recruited. Bier’s block was achieved using ropivacaine in to which either 10ml of 15% magnesium sulphate or 1 µg/kg dexmedetomidine was added. There was no significant difference between the two groups regarding the onset or recovery of motor blockade. However, the onset of sensory block was significantly shortened in the dexmedetomidine group (p<0.01).Also the sensory block recovery time was prolonged in the dexmedetomidine group, which was significant.(p<0.01).VAS score for tourniquet pain was lower in the dexmedetomidine group.(p<0.001). Perioperatively, there was a significant reduction in the number of patients requiring rescue analgesia and its consumed amount in the dexmedetomidine group compared to magnesium sulphate group. The quality of anesthesia was significantly better in the dexmedetomidine group compared to magnesium sulphate group. Patients in the dexmedetomidine group were more sedated briefly post-operatively. This study revealed that adding dexmedetomidine to ropivacaine during bier’s block as an adjuvant is better than magnesium sulphate.