Title: Clinicohematological Evaluation in Pancytopenic Patients
Authors: Ankita Mittal, Sonali Bandil, Anish Kumar, Seema Awasthi, Shyamoli Dutta
DOI: https://dx.doi.org/10.18535/jmscr/v6i1.132
Abstract
Pancytopenia is a clinicopathological entity which is commonly encountered in clinical practice. Since it is a striking feature for many serious clinical disorders, a proper intervention is required to avoid complications in these patients.
Objectives: To evaluate different conditions causing pancytopenia on the basis of clinic-hematological parameters.
Material and Methods: A Prospective study was conducted in the department of Pathology in TMMC&RC, Moradabad during the period of August 2015-August 2016. 100 Pancytopenic patients were evaluated on clinical and hematological background.
Result: Among 100 cases study, age ranged from 2-75 years with mean age of 38 years and male predominance. Most of the patients present with pallor, generalized weakness and fever. Hepatospleenomegaly followed by generalized weakness and bony tenderness were observed as physical findings. Megaloblastic anemia was the predominant finding in various causes of pancytopenia followed by mixed nutritional anemia, hypoplastic anemia, acute leukemia and reactive plasmacytosis.
Conclusion: This study shows that detailed hematological investigations along with bone marrow examination, is helpful to rule out the various causes of pancytopenia for further management in appropriate time.
