Title: Analysis of Lesions of Colon- A Histopathological Study
Author: Jay Prakash
DOI: https://dx.doi.org/10.18535/jmscr/v6i1.46
Abstract
Background: Colon lesions are quite common in population. The risk for developing invasive colorectal cancer increases with age, with more than 90% of new cases being diagnosed in patients older than 50 years. The present study analyzed the lesions of large intestine.
Materials & Methods: It included 136 specimens which included both resected specimens and biopsies submitted to the department. All biopsies and resected specimens received were immediately fixed in 10% formalin for 24 h. Gross features of specimen were noted, and multiple sections were taken.
Results: Maximum lesions were seen in age group 40-60 followed by 60-80, 20-40 and 0-20 years. Out of 136 lesions, 70 were neoplastic and 66 were non neoplastic and out of 70 neoplastic lesions, 14 were benign and 56 were malignant. Non neoplastic lesions were chronic colitis, tuberculous, ischemic colitis, inflammatory polyp (8) and inflammatory bowel disease (14). Benign lesions were inflammatory polyp (6), adenomatous polyp (4) and juvenile polyp (4). Malignant lesions were well differentiated adenocarcinoma (15), moderately differentiated adenocarcinoma (13), poorly differentiated adenocarcinoma (10), mucinous adenocarcinoma (12) and signet ring adenocarcinoma (6).
Conclusion: Most common seen lesions were neoplastic and maximum were malignant. Among malignant, well differentiated adenocarcinoma was mostly seen. Age group 40-60 years showed higher prevalence rate.
Keywords: Colon, Benign, Malignant.
