Abstract
Colorectal cancer (CRC) is one of the most common cancers worldwide and its incidence is reported to beincreasing probably due to the acquisition of a western lifestyle.
Methods: A retrospective study has been conducted to find the age, gender, site of lesion, clinical presentation, type of surgery, histology of lesion of colorectal cancer patients registered in National Cancer Institute of Sabratha between January to December 2013.
The aim of our research is to study the basic demography age, gender and anatomical location of the tumor in patients with CRC registered in National Cancer Center of Sabratha from January to December 2013.
Results: during Jan-Dec 2013, 135 cases of adenocarcinoma of colorectum were identified from our registry. The demographic characteristics of the patients are shown in Table 1. Age-stratified incidence of CRC showed that majority of the cases were in the age group 51-60 years (31.9%), followed by 41-50 years (21.5%). There were 13 (9.6%) cases of CRC below the age of 40 years. Ninety five (70.5%) patients presented with bleeding per rectum, 86 (63.7%) had lost significant weight, 73 (52%) had constipation, 70 (51.8%) had anorexia and another 49(36%) had a pabable mass.
Conclusion: Our finding is comparable to that of international figures: in that most of the CRCs were in distal parts, the incidence of CRC increases with age and the predominance of male.
Keywords: Colorectal Cancer, clinicodemografic, Sabratha.
References
- Boyle P, Langman JS. ABC of colorectal cancer: Epidemiology. BMJ 2000; 321:805–8.
- Goh KL, Quek KF, Yeo GT, et al. Colorectal cancer in Asians: a demographic and anatomic survey in Malaysian patients undergoing colonoscopy. Aliment Pharmacol Ther 2005;22:859–64.
- Mohandas KM, Desai DC. Epidemiology of digestive tract cancers in India. V. Large and small bowel. Indian J Gastroenterol 1999; 18:118–21.
- Zafar SY, Abernethy AP, Abbott DH, et al. Comorbidity, age, race and stage at diagnosis in colorectal cancer: a retrospective, parallel analysis of two health systems. BMC Cancer 2008; 8:345.
- Pal M. Proportionate increase in incidence of colorectal cancer at an age below 40 years: an observation. J Cancer Res Ther 2006; 2:97–9.
- Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D: Global cancer statistics. CA Cancer J Clin 2011, 61:69–90.
- Kamangar F, Dores GM, Anderson WF: Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006, 24:2137–2150.
- Ferlay J, Bray F, Pisani P, Parkin D: GLOBOCAN 2002: Cancer Incidence, Mortality and Prevalence Worldwide. Lyon, France: IARC; 2004.
- Seleye-Fubara D, Gbobo I: Pathological study of colorectal carcinoma in adult Nigerians: a study of 45 cases. Niger J Med 2005, 14:167–172.
- Ojo OS, Odesanmi WO, Akinola OO: The surgical pathology of colorectal carcinomas in Nigerians. Trop Gastroenterol 1992, 13:64–69.
- Adesanya AA, da Rocha-Afodu JT: Colorectal cancer in Lagos: a criticalre view of 100 cases. Niger Postgrad Med J 2000, 7:129–136.
- Okobia MN, Aligbe JU: Pattern of malignant diseases at the University of Benin Teaching Hospital. Trop Doct 2005, 35:91–92
- Mitry E, Benhamiche AM, Jouve JL, Clinard F, Finn-Faivre C, Faivre J: Colorectal adenocarcinomain patients under 45 years of age: comparison with older patients in a well-defined French population. Dis Colon Rectum 2001, 44(3):380–387. 5.
- Guillem JG, Puig-La CalleJr J, Cellini C, Murray VM, Ng J, Fazzari M, Paty PB: Varying features of early age-of-onset‘ sporadic’ and hereditary non polyposis colorectal cancer patients. Dis Colon Rectum 1999, 42:36.
- H Boytchev, S Marcovic, GJ. Oettle The characteristics of large bowel cancer in the low-risk black population of the Witwatersrand. J R Coll Surg Edinb 1999;44:366-70.
- S Hoseini, L Moaddabshoar, S Hemati, M. Mohammadianpanah An overview of clinical and pathological characteristics and survival rate of colorectal cancer in Iran. Ann Colorectal Res 2014; 2:e17264.
- JC Hsiang, W Bai, D. Lal Symptom presentations and other characteristics of colorectal cancer patients and the diagnostic performance of the Auckland Regional Grading Criteria for Suspected Colorectal Cancer in the South Auckland population. N Z Med J 2013; 126:95-107.
- M Decastel, M Ossondo, AM Andrea. Colorectal cancer in patients seen at the teaching hospitals of Guadeloupe and Martinique: discrepancies, similarities in clinicopathological features, and p53 status. BMC Clin Pathol. 2014; 14:12.
- El Mistiri M, Verdecchia A, Rashid I, El Sahli N, El Mangush M, Federico M: Cancer incidence in eastern Libya: the first report from the Benghazi Cancer Registry, 2003. Int JCancer 2007, 120:392–397.
- Saidi HS, Karuri D, Nyaim EO: Correlation of clinical data, anatomical site and disease stage in colorectal cancer. East Afr Med J 2008, 85:259–262.
- Takada H, Ohsawa T, Iwamoto S, Yoshida R, Nakano M, Imada S, Yoshioka K, Okuno M, Masuya Y, Hasegawa K, Kamano H, Hioki K, Muto T, Koyama Y: Changing site distribution of colorectal cancer in Japan. Dis Colon Rectum 2002, 45:1249–1254.
- Ponz de Leon M, Marino M, Benatti P, Rossi G, Menigatti M, Pedroni M, Di Gregorio C, Losi L, Borghi F, Scarselli A, Ponti G, Roncari B, Zangardi G, Abbati G, Ascari E: Trend of incidence, sub-site distribution and staging of colorectal neoplasms in the 15-year experience of a specialized cance registry. Ann Oncol 2004, 15:940–946.
Corresponding Author
Ramadan Elamyal MD
Associate Prof., Consultant Surgeon, Misurata Cancer Center
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v5i11.225
