Abstract
Aim and Objectives: To assess the effect of oral clonidine and oral atenolol as premedication on hemodynamic stability, blood loss, quality of the surgical field and side effects in patients undergoing FESS.
Material and Methods: The study included total 100 patients of (age 15 – 50 years) ASA grade I and II were randomly divided into two groups of 50 each. Patients received oral clonidine 5mcg/kg in group C and oral atenolol 1mg/kg in group A, 90 minutes prior to induction. Induction and maintainence of general anaesthesia was performed by the same standard protocol for both groups. Various study parameters i.e. hemodynamic effect (PR, SBP, DBP & MAP), amount of total blood loss, quality of surgical field, sedation score and side effects were recorded and statistically analyzed.
Results: The hemodynamic stability, less amount of blood loss and good quality surgical field was obtained in clonidine group compared to that of atenolol group & there were no serious side effects both in the groups.
Conclusion: We conclude that oral clonidine is better than atenolol in terms of hemodynamic stability, lesser blood loss & quality of surgical field without any side effects.
Keywords: Atenolol, Clonidine, hemodynamic stability, Functional endoscopic sinus surgery (FESS).
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Corresponding Author
Vijay Patil
Assistant Professor, B J Medical College & Sasoon hospital, Pune
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v5i11.183
