To Evaluate the Role of Bone Marrow Aspiration Cytology in Megaloblastic Anaemia

Title: To Evaluate the Role of Bone Marrow Aspiration Cytology in Megaloblastic Anaemia

Authors: Dr M.A. Sameer, Dr Swapnil Galat, Dr S.A. Deshpande, Dr Manisha Ahuja

DOI: https://dx.doi.org/10.18535/jmscr/v5i11.146

Abstract

Background: Bone marrow aspiration plays a major role in the diagnosis of various haematological disorders. Bone marrow aspiration cytology is a proven method for the evaluation of haematological conditions, malignancies, storage disorders and some chronic systemic conditions. Peripheral blood smear examination and other routine laboratory assays are not always sufficient for diagnosis of various diseases which affect the blood and bone marrow. Bone marrow aspiration is useful in making out better individual cell morphology. This study was observational study carried out in the department of pathology of Dr. SCGMC, Nanded over a period of 2 years from May 2015 to May 2017. Bone marrow aspiration along with serum vitamin B12 levels were carried out in 50 suspected cases of megaloblastic anaemia. The aim of this study was to evaluate the role of bone marrow aspiration cytology and its relation to serum vitamin B12 levels in cases of megaloblastic anaemia.

Keywords: Bone marrow aspiration, Serum vitamin B12 levels, megaloblastic anaemia.

References

Malempati S, Joshi S, Lai S, Braner D, Tegtmeyer K. Bone marrow aspiration and biopsy. N Engl J Med. 2009;361:e28.
Hutchinson RE, McPherson RA, Schexneider KI. Hematology, Coagulation and Transfusion Medicine. In: McPherson RA &Pincus MR, editor. Henry’s Clinical Diagnosis and Management by Laboratory Methods, 22^nd Philadelphia: ELSEVIER SAUNDERS, 2011:557-600.
Gibson RS. Assesment of folate and vitamin B12 status. In: Gibson RS, editor. Principles of Nutritional Assesment. Second ed. Oxford: Oxford University Press; 1990;591-631.
Hoffbrand AV, Herbert V. Nutritional anaemias. Semin Hematol 1999; 36(7): 13-23.
Nora CJS, Wang J, Glassy EF. Bone marrow In: Silverberg SG, editor. Silverberg’s Principles and Practice of Surgical Pathology and Cytopathology. 4^th Philadelphia: Churchill Livingstone Elsevier; 2006: 619.
Ralph C. Megaloblastic anaemias: disorder of impaired synthesis In: John PG &Danial AA, editors. Wintrobe’s Clinical Hematology, 13^th Philadelphia: Lippincott Williams & Wilkins, 2009.
Reisner EH. The nature and significance of megaloblastic blood formation.Blood. 1958;13:313-332.
Chanarin I, Metz J. Diagnosis of cobalamin deficiency : the old and new. Br J Haematology 1997;97:695-700.
Kasper DL, Braunwald E, Fauci A, Hauser S, Longo D, Jameson JL. Harrison’s principles of internal medicine. 16^thed. New York: McGraw-Hill Medical Publishing Division;2005

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