Abstract
Aggressive angiomyxomas are rare, locally invasive mesenchymal tumours, usually occurring in the pelvis or perineum of young women. They can be locally aggressive and have high risk of local relapse. The authors present a case of a postmenopausal woman with a five-year, slow growing, large, pedunculated mass on the right labia majora. Histological exam after surgical excision concluded it was an aggressive angiomyxoma. There was no local relapse after two years of follow-up.
Keywords: Aggressive angiomyxoma, vulvar, genital, menopause.
References
- Han-Geurts IJ, van Geel AN, van Doorn L, M den Bakker, Eggermont AM, Verhoef C. Aggressive angiomyxoma: Multimo-dality treatments can avoid mutilating surgery. Eur J Surg Oncol. 2006;32:1217– 21.
- Siassi RM, Papadopoulos T, Matzel KE. Metastasizing aggressive angiomyxoma. N Engl J Med. 1999;341:1772.
- Blandamura S, Cruz J, Faure Vergara L, Machado Puerto I, Ninfo V. Aggressive angiomyxoma: A second case of metastasis with patient's death. Hum Pathol. 2003;34:1072–4.
- Lin HC, Liu CC, Kang WY, Ke HL, Li CC, Wu WJ, Huang CH. Huge aggressive angiomyxoma: a case report and literature review. Kaohsiung J Med Sci. 2006;22:301–304.
- Fishman A, Otey LP, Poindexter AN, Shannon RL, Gritanner RE, Kaplan Al. Aggressive angiomyxoma of the pelvis and perineum. A case report. J Reprod Med. 1995;40:665–669.
- Wolf CA, Kurzeja R, Fietze E, Buscher U. Aggressive angiomyxoma of the female perineum in pregnancy. Acta Obstet Gynecol Scand. 2003;82:484–485.
- Chen H, Zhao H, Xie Y, Jin M. Clinicopathological features and differential diagnosis of aggressive angiomyxoma of the female pelvis - 5 case reports and literature review. Medicine Clinical Case Report. 2017;96:20.
- Das BP, Baruah D, Medhi KB, Talukder B. An aggressive angiomyxoma of vulva - A rare entity - A case report. J Midlife Health. 2016;7(3):140–143.
- McCluggage WG, Patterson A, Maxwell P. Aggressive angiomyxoma of pelvic parts exhibits estrogen and progesterone receptor positivity. J Clin Pathol. 2000;53:603–605.
- Bagga R, Keepanasseril A, Suri V, Nijhawan R. Aggressive Angiomyxoma of the Vulva in Pregnancy: A Case Report and Review of Management Options. MedGenMed. 2007;9(1): 16.
Corresponding Author
José Pedro Coutinho Borges
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