Title: A Study on Prevalence, Risk Factors of Multi Drug Resistant Organism and its Impact in Diabetic Foot
Authors: Dr B.Deni Raja, Dr V.R.Baskaran, Dr V.Natarajan, Dr R.Renjith Singh
DOI: https://dx.doi.org/10.18535/jmscr/v5i11.54
Abstract
India is considered to be the diabetic capital of the world. Almost 15% of the diabetics are prone for ulcers in their lifetime Diabetic foot ulcer remains a serious medical problem, which is extremely difficult to heal and exhibits a high recurrence rate. The major concern in this diabetic foot at present is the increasing incidence of multidrug resistant organisms. This study was done to know the prevalence, risk factors of MDRO and its impact on wound healing. The study sample was 150 diabetic foot patients admitted in surgery department, Rajah Muthiah Medical College, Chidambaram. In our study 66 % of the ulcers grew multi-drug resistant organisms (MDRO) and 54.8% of isolated organisms were multi drug resistant. Poor glycaemic control, previous hospitalisation, previous history of amputation, previous antibiotic usage, larger ulcer, necrotic ulcer, recurrent ulcers, higher grade of ulcer, presence of osteomyelitis, presence of retinopathy, peripheral vascular disease, neuropathy and polymicrobial culture, were significantly associated with MDRO infected foot ulcers. However, analysis by logistic regression revealed that only the recurrent ulcers and higher grade of ulcers were significantly associated with multi-drug resistant organism infections. The presence of MDRO does not have any impact on wound healing but it is associated with longer duration of hospital stay and increased rate of amputations.
Keywords: Diabetic foot, Multidrug resistant organism (MDRO).
