Abstract
Introduction: Prevalence of coronary heart disease (CHD) is rising at rapid pace among urban as well as rural population in India due to rise in prevalence of major cardiovascular risk factors. An important change in risk factor pattern is more rapid rise in risk factors for CHD among rural and slum population in comparison with urban population in India. Present hospital based study was conducted to evaluate the clinical profile, presentation, risk factors and lipid profile of patients with AMI from rural area.
In this observational study, 50 patients with definite evidence of acute myocardial infarction (AMI) were studied with reference to clinical profile and risk factors. In detail medical, personal, family and past history was explored and socio-demographic data was recorded. After complete physical examination and ECG, blood samples were collected for biochemical assays.
Results: Out of 50 patients, 41 were male and 9 female with mean age 54.74 +/- 21.3 years. Sweating with chest pain was the most common presenting symptom. Either single or multiple risk factors like smoking, hypertension, dyslipidemia, are more prevalent. Surprisingly 74% of the cases were non-obese. Inferior and anterior wall infarcts were more common. Rhythm disturbances and left ventricular failure (LVF) were the most common complication.
Our study findings suggest clustering of multiple traditional risk factors. There was clustering of multiple traditional risk factors like smoking, hypertension, dyslipidemia, diabetes, male sex, and advanced age.
Keywords: Acute myocardial infarction, rural India, dyslipidemia, hypertension, clinical profile.
References
- Rajeev Gupta, Indu Mohan, Jagat Narula.Trends in Coronary Heart Disease Epidemiology in India Annals of global health 2016. 82(2) 307-315.
- Yusuf, Salim et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study The Lancet , Volume 364 , Issue 9438 , 937 – 952
- Zodpey Sanjay P, Shrikhande Sunanda N, Negandhi Himanshu N, Ughade Suresh N, Joshi Prashant P Risk factors for acute myocardial infarction in Central India: A case-control study Indian Journal of community medicine 2015;40:19-26
- Sushma Pandey , Suresh Pandey , Purushottam Jhanwar ,. Anshul JhanwarA prospective study of Myocardial Infarction patients admitted in a tertiarycare hospital of south-eastern Rajasthan Int J Biol Med Res. 2012; 3(2): 1694-1696
- Deb S, Dasgupta A .A study on risk factors of cardiovascular diseases in anurban health centre of Kolkata. Indian J Commun Med 2008; 33: 265-7.
- Shantirani CS, Pradeepa R, Deepa R. Prevalence and risk factor ofhypertension in a selected south Indian population. The Chennai urbanpopulation study.2003; 51:20-7.
- Bonita R, Courten M, Dwyer T, Jamrozik K. Surveillance of Risk Factors forNon-communicable Disease; WHO STEP wise Approach. Geneva: WHO,2001.
- Executive summary of the Third Report of the National Cholesterol Education Prog-ram (NCEP) (2001) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 285: 2486–2497.
- Nag T, Ghosh A. Cardiovascular disease risk factors in Asian Indian population: A systematic review. Journal of Cardiova-scular Disease Research. 2013;4(4):222-228. doi:10.1016/j.jcdr.2014.01.004.
- Wang, H.J. Chen, S. Shaikh, P. MathurIs obesity becoming a public health problem in India? Examine the shift from under- to over-nutrition problems over time Obes Rev, 10 (2009), pp. 456-47.
- Clara KC, Naidus S, Raju K. Significant lipid, adiposity and metabolic abnormalities amongst 4535 indians from a developing region of ruralAndhra Pradesh.2008;196:193-200.
- Misra A., Luthra K., Vikram N.K. Dyslipi-demia in Asian Indians: determinants and significance. J Assoc Physicians India. 2004;52:137–142. [PubMed]
- Krishnan MN. Coronary heart disease and risk factors in India – On the brink of an epidemic? Indian Heart Journal. 2012;64 (4):364-367. doi:10.1016/j.ihj.2012.07.001.
- Misra, N. Singhal, B. Sivakumar, N. Bhagat, A. Jaiswal, L. Khurana Nutrition transition in India: secular trends in dietary intake and their relationship to diet-related non-communicable diseases J Diabetes, 3 (2011), pp. 278-292
- Joshi R., Cardona M., Iyengar S. Chronic diseases now a leading cause of death in rural India–mortality data from the Andhra Pradesh Rural Health Initiative. Int J Epidemiol. 2006;35:1522–1529. [PubMed]
Corresponding Author
Dr Ashish Deshpande
Professor Department of Cardiology M.G.M Medical College Aurangabad
Contact Number: 919420763430, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.