Abstract
Background: The burden of tuberculosis and diabetes mellitus is significantly high in India. People with diabetes are at higher risk of developing active tuberculosis. The main purpose of this study is to determine prevalence of diabetes and pre-diabetes among TB cases. As the risks of treatment failure, death and reactivation are high in TB-DM patients, we had also included study of clinical profile of these patients.
Material and Method: We have done a prospective study over a period of two years. Study size was 1000 TB patients diagnosed at our institute. All willing patients above the age of 12 years were included in our study. We followed WHO criteria with Fasting glucose level (FGL) for diagnosis of diabetes and pre-diabetes. Tuberculosis patients with FGL more than /equal to 110 mg/dl were evaluated in details to study their clinical profile. Outcomes of these patients were noted from TB registers/records.
Result: Out of 1000 TB patients, 212 patients had impaired FGL. Among them, 80 TB patients had diabetes and 132 TB patients had pre diabetes. 15% among the 212 patient were previously diagnosed cases of diabetes mellitus on treatment. Impaired FGL was significantly associated with age group 31 to 45 years, male predominance, low socio economical status. Pulmonary tuberculosis and sputum positivity was common. Pleural TB was the most common type of extra-pulmonary tuberculosis seen. Out of 212, only 7 patients died before completion of DOTS under RNTCP.
Conclusion: In our study, the prevalence of diabetes is 8% and pre-diabetes is 13.2%. TB –DM patient pre-dominantly seen in age of group of 31-45 yrs TB-DM patient commonly had infective form of tuberculosis. Outcome of these patients on DOTS under RNTCP is significantly good. Screening patient with TB for FGL will definitely help in early detection of diabetes mellitus.
Keywords: Diabetes, Pre-diabetes, Tuberculosis, prevalence.
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Corresponding Author
Dr Anita Saibannavar
Associate Professor and Head, Department of Pulmonary Medicine,
R.C.S.M.G.M.C., Kolhapur
DOI: https://dx.doi.org/10.18535/jmscr/v5i8.181
