Abstract

Background: Dyslipidemia is one of the common disorders seen in most of the diabetes patients. Objective: To study the lipid profile in patients with diabetes mellitus. 

Methods: The study was carried out at a diagnostic and research centre for a period of one year. The study included 100 diabetic patients and 100 healthy  subjects .Their serum samples were assessed for fasting blood glucose , total cholesterol , triglycerides, low density lipoprotein(LDL) cholesterol  and high density lipoprotein(HDL) cholesterol  by using standard biochemical methods after taking informed consent.

Results: Out of 100 diabetic patients 45 (45%) were males and 55 (55%) were females. 75 patients presented with type 2 diabetes mellitus(DM) and 25 patients with type 1 diabetes mellitus. Maximum number of patients were in age group of 20-30 years in type-1 and 45-65 years in type-2 diabetes mellitus. 85.3% of type 2 DM patients showed high serum cholesterol level, while only 32% of the type 1 DM patients showed high serum cholesterol level. 80% of type 2 DM patients showed high serum triglyceride level, while 60% of type 1 DM subjects showed high triglyceride level. Serum LDL level was high in 48% of type 2 DM patients, while only 16% of type 1 DM patients showed higher value. 40% of type 1 DM patients showed low(<40 mg/dl) serum HDL value while all patients of type 2 had low serum HDL level.

Conclusion: The frequencies of the high cholesterol, high TG , high LDL with low HDL levels were higher in the diabetic group, thus indicating that diabetic patients were more prone for dyslipidemia, which  is a major risk factor for cardiovascular disorders.

Keywords-dyslipidemia, diabetes mellitus, serum cholesterol, serum LDL, serum HDL, serum triglyceride.