Abstract
Introduction: Urinary tract infections (UTI) are one of the most common infectious diseases. In a limited resource setting, the availability of and accessibility to the new generation higher antibiotics is always a cause for concern. this study was conducted in patients with uncomplicated UTIs to evaluate the microbial growth pattern obtained from the urine specimens and their corresponding antibiotic sensitivity profile using conventional antibiotics
Materials and Methods: A prospective cross sectional study was conducted in a Government Medical College in Chennai comprising of 296 patients with clinically suspected UTI. Urine samples were collected and subjected to standard culture and sensitivity testing. SPSS software (version 16) was used to analyse the data. Simple descriptive statistics, Kruskal Wallis test and Man Whitney U post hoc tests were carried out. P<0.05 was considered significant.
Results: E.coli was the most common organism isolated in 66 out of total 296 samples (22.3%), followed by Enterobacter (2.7%). For E.coli, Amikacin was the drug to which most cultures (62.1%) were sensitive, followed by Cotrimoxazole (31.8%) and Nitrofurantoin (25.8%). For Enterobacter species, Gentamycin, Amikacin and Nitrofurantoin were equally sensitive (50%)
Conclusion: E.Coli is responsible for a vast majority of UTI and that Amikacin can be used as an empirical first line antibiotic for UTI in males and females in a limited resource setting where higher and newer antibiotics are not available
Keywords: UTI, E.coli, Amikacin.
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DOI: https://dx.doi.org/10.18535/jmscr/v5i7.202
