Abstract
Objective: To highlight variable clinical presentation and management of 4 cases of atypical Mooren’s ulcer.
Design: Retrospective case series.
Methods: Patients presenting with bilateral peripheral ulcerative lesions were reviewed. A diagnosis of Mooren’s ulcer was made after extensive medical and laboratory testing to rule out any infectious or systemic cause. All patients were managed medically or surgically according to their severity and response to treatment. Four patients between 20-40 years of age who were diagnosed as bilateral atypical Mooren’s ulcer were included in the series.
Results: 2 cases responded well to medical management with systemic and topical steroids, cyclosporine eye drops and autologous serum. Two cases with aggressive course were managed surgically with conjunctival resection and amniotic membrane transplantation with cyanoacrylate glue application in areas of deep excavation. Systemic immunosuppressants were not required in any of the cases.
Conclusion: Atypical Mooren’s ulcer presents as a bilateral disease in young patients and can progress very rapidly to perforation. However, with timely and appropriate treatment, the ulcers can be managed and eyes can be salvaged, minimizing the visual loss.
Keywords: Atypical Mooren’s ulcer; Bilateral; Peripheral ulcerative keratitis; Autologous serum; Amniotic membrane; Cyanoacrylate glue.
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DOI: https://dx.doi.org/10.18535/jmscr/v5i7.162
