Abstract
Spinal anaesthesia is frequently used for both optional and emergency caesarean section. Anesthesia‑related mortality is decreased when general anesthesia is avoided. The study has planned with the aim to assess the clinical efficacy of Levobupivacaine compared with racemic Bupivacaine in spinal anesthesia for lower abdominal, pelvic and lower limb surgeries.
The total 50 enrolled patients were divided in 2 groups. Group A included the 50 patients received 3ml of 0.5% Levobupivacaine (15mg) 5mg/ml. Group B patients received 3ml of 0.5% Bupivacaine (15mg) 5mg/ml.
From the present study we conclude that, the time for onset of sensory and motor block showed nostatistical significance in both groups. The duration of motor block was shorter, resulting in early ambulation in Levobupivacaine group. Haemodynamic parameters were stable in the Levobupivacaine group when compared with the Bupivacaine group. Fewer episodes of hypotension and bradycardia and other side effects were observed in Levobupavaine group.
Keywords: Spinal anaesthesia, Levobupivacaine, Bupivacaine, comparative study etc.
References
1. Bronwen Jean Bryant; Kathleen Mary Knights (2011). Pharmacology for Health Professionals. Elsevier Australia. pp. 273–. ISBN 978-0-7295-3929-6.
2. Burlacu CL, Buggy DJ (April 2008). "Update on local anesthetics: focus on levobupivacaine". Ther Clin Risk Manag. 4 (2): 381–92. PMC 2504073 Freely accessible. PMID 18728849.
3. Gulec D (Apr 2014). "Intrathecal bupivacaine or levobupivacaine: which should be used for elderly patients?.". J Int Med Res. 42 (2): 376–385. PMID 24595149. doi:10.1177/0300060513496737.
4. Lexicomp. "Bupivacaine (Lexi-Drugs)". Retrieved 20 April 2014.
5. Miller, Ronald D. (November 2, 2006). Basics of Anesthesia. Churchill Livingstone.
6. Guler, Gulen, et al. "A comparison of spinal anesthesiawith levobupivacaine and hyperbaricbupivacaine for cesarean secti-ons: A randomized trial." Open Journal of Anesthesiology, Vol.2 No.3 (2012).
7. Andrea Casati, Elena Moizo, Chiara Marcheti et al,Prospective randomized doubleblindcomparison ofunilateral spinal anaesthesia with hyperbaric bupivacaine, ropivacaine & levobupivacaine for inguinal herniorraphy. Anaes. Anal.; 2004;99;1384-92.
8. M Mantouvalou, S Ralli, H Arnaoutoglou, G Tziris and G Papadopoulos. Spinal anesthesia: Comparison of plain Ropivacaine, bupivacaine and levobupiva-caine for lower abdominal surgery. Acta Anaesth. Belg.,2008,59,65-71.
9. Sathitkarnmanee T1, Thongrong C, Tribuddharat S, BnMT, Bn KP, Bn RK.: Acomparison of spinal isobariclevo-bupivacaine and racemic bupivacaine for lower abdominal and lower extremity surgery; J Med Assoc, Thai. 2011Jun 94(6):716-20.
10. F Fattorini, Z Ricci et al; levobupivacaine versus racemicbupivacaine for spinal anaesthesia in major orthopaedicsurgery; Minerva Anestesiol 2006;72:637-44.
11. Hakan Erbay R, Ermumcu O, Hanci V, Atalay H.Acomparison of spinal anesthesia with low-dose hyperbariclevo-bupivacaine and hyperbaric bupivacaine for transurethral surgery:a randomized controlled trial. Minerva Anestesiol. 2010;76:992–100.
Corresponding Author
Dr Rajeev Kumar
Assistant Professor, Department of Anesthesia, Shri Ramkrishna Institute of Medical Sciences & Sanaka Hospitals, Durgapur, WB, India
DOI: https://dx.doi.org/10.18535/jmscr/v5i7.159
