Title: Corelation of Sehgal Index and Rbc Indices For Screening of Beta Thalassemia Trait
Authors: Ujwala Maheshwari, Amruta Padhye, Parineeta Samant, Reeta Dhar
DOI: https://dx.doi.org/10.18535/jmscr/v5i7.37
Abstract
Background: Hemoglobinopathies are a group of disorders of hemoglobin synthesis characterized by the absence or reduction of one or more of the globin chains of hemoglobin.
Materials and Methods: This is an observational study conducted at the department of Pathology at MGM Hospital, Navi Mumbai. A total number of 72 samples were obtained and run on HPLC (BIORAD D10) over a period of 6 months from January 2016 – June 2016.
Objectives: To evaluate the Sehgal index and compare it to the CBC based indices for best combination of sensitivity and specificity for the prediction of beta thalassemia trait.
Result and Conclusion: In our study, the percentage of beta thalassemia trait in the study group was 20.83.
Keywords: sehgal index, beta thalassemia trait, rbc indices.
