Title: Evaluation of Quality of Life and Medication Adherence in Type-II Diabetic Patients
Authors: G.Swathi, Dr.P.Kishore, Dr Saini Venkateshwarulu, R. Deepthi
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.168
Abstract
Diabetes mellitus is the most common metabolic disorder in the world. In India, the prevalence rates of diabetes has increased dramatically since the first national survey was undertaken (1971). At that time the prevalence was 2.3% in ur an areas and 1.2% in rural areas. The most recent studies suggest prevalence rates between 15 to 20% in urban areas and around 5% in rural areas. Acute and long term complications of T2DM has effect on health related quality of life. Thus Quality of Life (QoL) has emerged as an important factor for assessing severity of chronic diabetes. Symptoms like dragging limbs, weakness, burning feet among individuals with chronic and uncontrolled diabetes provides valuable information about their medication adherence status and blood sugar levels. Variables such as HbA1c, diet adherence, self-care activities give an insight on medication adherence. Counselling patients regarding awareness and lifestyle modifications among diabetic and non-diabetic can reduce the prevalence of this chronic disease. The present study was conducted in care diabetes centre, Warangal region for 6 months period with a study population of 300.Patient’sresponse against the pre-framed questionnaire was noted with an informed consent. The QoL was assessed by World Health Organization BREF instrument and medication adherence was calculated by Moriskyscale. QoL of 59.09% diabetics were found to be under average category and 62.3% diabetics were in high adherence category, reason being they were on fixed dose combinations.
Keywords: Type-2 diabetes, Quality of Life, WHO QoL-BREF, medication adherence, morisky scale, HbA1C.
1. Elizabeth A. Hacketl and Stephen N.J.Jackson. Chapter -44 Diabetes mellitus. Text book of Clinical pharmacy and therapeutics. Roger Walker 5th edition; Page no: 685-694.
2. Mohammed MansorManan, Akhma Radzuanna Husin, Ali SalehAlkhoshaiban, Yaser Mohammed Ali Al –Worafi, Long Chiau Ming. Interplay between oral hypoglycemic medication adherence and quality of life among elderly type-2 diabetes DM patients. Journal of clinical and diagnostic research. 2014 december, volume-8 (12); page no: JC 05-JC 09.
3. Manjusha Sajith, Madhu Pankaj, Atmatam Pawar, AmitModi, Ronak Sumariya. Medication adherence to antidiabetic therapy in patients with type-2 DM. International journal of pharmacy and pharmaceutical sciences. 2014; volume 6; suppl-2; page no: 565-570.
4. World health day- 7th April 2016- diabetes. http://www.searo.who.int/india/2016/en.
5. V Mohan, S sandeep. Epidemiology of type 2 diabetes: Indian scenario. Indian J Med Res 2007 March; 217-230.
6. WHOQOL-BREF, introduction, administration, scoring and generic version of assessment. Programme on mental health, world health organization, Geneva. Field trial version; December 1996.
7. Volpato S, Maraldi C, Fellin R. Type 2 diabetes and risk for functionaldecline and disability in older persons. Curr Diabetes Rev.2010;6:134–43.
8. Sundaram M, Kavookjian J, Patrick JH, Miller LA, MadhavanSS,ScottVG.Quality of life, health status and clinical outcomes in type 2 diabetes patients. Qual Life Res. 2007;16:165–77.
9. Belapatel, BhavitOza, Kamlesh Patel, SupriyaMalhotra, Varsha Patel. Health related quality of life in type-2 diabetic patients in western India using World Health organization quality of life-BREF and appraisal of diabetes scale. International journal of diabetes in developing countries; 2014, vol34(2); pg no:100–107.
10. Harish kumarsomappa, Mahesh Venkatesha, Raghavendra Prasad. Quality of life assessment among type-2 Diabetic patients in rural tertiary centre, International journal of medical science and public health. 2014; vol 3; issue 4; pg no: 415-417.
11. G.parthasarathi, Karinnyfort-Hansen, milap C nahata. Chapter-6 Medication adherence. A textbook of clinical pharmacy practice, essential concepts, and skills; pgno-54-58.
12. Barbara G.wells, Joseph T.Dipiro. Section-4. Chapter-19 Diabetes mellitus. Text book of pharmacotherapy handbook. 7th edition; pg no: 210-214.
13. Boon-How Chew, Noor-Hasliza Hassan, Mohd-SidikSherina. Determinants of medication adherence among adults with type 2 diabetes mellitus in three Malaysian public health clinics: a cross- sectional study. Patient preference and adherence. 2015; vol-9; pg no: 639-648.
14. Aliasghar A Kiadaliri, BaharakNajafi and MaryamMirmalek-Sani. Quality of life in people with diabetes: a systematic review of studies in Iran. Journal of Diabetes & Metabolic Disorders 2013, 12:54, pg no: 2-10.
15. Mohammed MansorManan, Akhma Radz-uanna Husin, Ali Saleh Alkhoshaiban, Yaser Mohammed Ali Al –Worafi, Long Chiau Ming. Interplay between oral hypoglycemic medication adherence and quality of life among elderly type-2 diabetes DM patients. Journal of clinical and diagnostic research. 2014 december, volume-8 (12); page no: JC 05-JC 09.
16. BA Kolawole, SK Mosaku, and RT Ikem. A Comparison of two measures of quality of life of Nigerian clinic patients with type 2 Diabetes Mellitus. African Health Sciences 2009; 9(3): 161-166.
17. Cheah WL, Lee PY, Lim PY, Fatin Nabila AA, Luk KJ, NurIrwana AT. Perception of quality of life among people with diabetes. Malaysian Family Physician 2012; Volume 7, Number 2 & 3.
18. Alan Chait, and Karin E. Bornfeldt. Diabetes and atherosclerosis: is there a role for hyperglycemia. Journal of Lipid Research, April Supplement, 2009. S335-S339.
19. Bani-Issa W. Evaluation of the health-related quality of life of Emirati people with diabetes: integration of sociodemographic and disease-related variables. Eastern Mediterranean Health Journal. 2011; vol-17; pg no: 825-830.
20. BA Kolawole, SK Mosaku, and RTIkem. A Comparison of two measures of quality of life of Nigerian clinic patients with type 2 Diabetes Mellitus. African Health Sciences 2009; 9(3): 161-166.
21. Arulmozhi’s, Mahalakshmy T. Self care and medication adherence among type 2 diabetics in Puducherry, southern India: A Hospital based study. Journal of clinical and diagnostic research.2014 April; vol-8(4); UC01-UC03.