Abstract
Phlyctenular keratoconjunctivitis (PKC) is a type IV cell mediated hypersensitivity reaction to endogenous microbial proteins. It is relatively more common in the paediatric age group in association with pulmonary and lymph node tuberculosis.1 Many antigens like staphylococcal products, worm infestation, fungi, viruses, and parasites but the main antigen responsible for PKC was tuberculoprotein.2-6 We report a case of PKC in a patient who was Mantoux test positive but no other clinical features of tuberculosis.
References
1. Bhandari A, Bhandari H, Shukla R, et al. BMJ Case Rep 2014;doi:10.1136/ bcr-2013-202010.
2. Rohatgi J, Dhaliwal U. Phlyctenular eye disease: A reappraisal. Jpn J Ophthalmol. 2000;44:146–50.
3. Culbertson WW, Huang AJ, Mandelbaum SH, Pflugfelder SC, Boozalis GT, Miller D. Effective treatment of phlyctenular keratoconjunctivitis with oral tetracycline. Ophthalmology. 1993;100:1358–66.
4. Jeffrey MP. Ocular diseases caused by nematodes. Am J Ophthalmol. 1995;40:41–52.
5. Hussein AA, Nasr ME. The role of parasitic infection in the aetiology of phlyctenular eye disease. J Egypt Soc Parasitol. 1991;21:865–8.
6. Thygeson P. The etiology and treatment of phlyctenular keratoconjunctivitis. Am J Ophthalmol. 1951;34:1217–36.
7. Gautam P, Shrestha GS, Sharma AK. Phlyctenular keratoconjunctivitis among children in the tertiary eye hospital of Kathmandu, Nepal. Oman Journal of Ophthalmology. 2015;8(3):147-150. doi:10.4103/0974-620X.169884.
8. Singal A,Aggrawal P,Pandhi D,Rohatgi J.Cutaneous tuberculosis and phlyctenular keratoconjunctivitis: A forgotten association. Indian J Dermatol Venereol Leprol 2006;72:290-2.
9. Doan S, Gabison E, Gatinel D, Duong MH, Abitbol O, Hoang-Xuan T. Topical cyclosporine A in severe steroid-dependent childhood phlyctenular kerat-oconjunctivitis. Am J Ophthalmol. 2006; 141:62–66.
Corresponding Author
Dr Santosh Kumar
F-110, New Doctors Hostel, MGM Campus, Kishanganj, Bihar
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.147
