Title: Role of Computed Tomography in Diagnosis of Bronchogenic Carcinoma with Histopathological Correlation
Authors: Dr Adaikkalavan C, Dr Sajitha K, Dr Josey Verghese, Dr Amilu Elsa Varghese
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.116
Abstract
Background: In India, lung cancer is the commonest and most lethal cancer among males accounting for 10.9% of all cancer cases and 13% of cancer related mortality. Computed tomography is the modality of choice for evaluating bronchogenic carcinoma. CT has a role in identifying the lung nodules and characterizing them as benign or malignant. CT guided FNAC of lung lesions has rapidly emerged as less invasive, cheap, rapid & fairly accurate diagnostic aid in lung lesions. The present study is aimed at evaluating the imaging characteristics of pulmonary mass lesions by CT along with CT guided FNAC/ bronchoscopy guided biopsy of the lesions for histopathological correlation thereby aiding patients in correct diagnosis and thereby aiding patients with appropriate treatment also.
Materials and methods: Data was collected from 53 patients with clinically or radiologically suspected pulmonary mass lesion referred for CT scan of thorax to Department of Radiodiagnosis. Contrast study is done, lung lesions were characterized and CT guided FNAC done in our Department using 22G Spinal needle under local anaesthesia. Collected data were analysed based on the variables of the lung lesion seen in CT images followed by CT diagnosis and correlation made with histopathology report.
Conclusion: CT guided FNAC is a simple, less invasive and effective method to obtain Histopathology thereby prompting appropriate management. CT is a highly sensitive test (95.83%) and also has a high positive predictive value (97.87%) to diagnose Bronchogenic carcinoma in a sample suitably selected and referred for malignancy. Diagnostic work up by CT with guided FNAC may help the patient in correct diagnosis and thereby prompting appropriate management.
Keywords: Bronchogenic carcinoma, CT guided FNAC, Bronchoscopy guided biopsy
