Title: A Comparative Study of Intubating Conditions and Cardiovascular Effects of Rocuronium and Succinylcholine in Rapid Sequence Induction and Intubation
Authors: Ibemhal Heisnam, K.Sarda Devi, S.Thoibahenba Singh, K. Upendra Singh, Rakesh Nongthombam
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.88
Abstract
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Aim of Study: Succinylcholine is the most frequently used muscle relaxant for rapid sequence intubation but sometimes the need arises to use another agent. The aim of our study is to compare the haemodynamic profile and intubating conditions of rocuronium with that of succinylcholine during rapid sequence induction and intubation. Material and Methods: 80 patients posted for emergency surgical procedure under general anaesthesia were randomly divided into two groups A & B. A rapid sequence induction and intubation were done in all the patients. Group a patients received 0.6mg/kg rocuronium and Group B received 1.5mg/kg succinylcholine. Intubation was done at 60 seconds after the administration of muscle relaxant and intubating conditions was graded according to Copenhagen Consensus Conference Rating Scale. The haemodynamic parameters (pulse rate& blood pressure) were recorded and compared. Results: In both the groups pulse rate and blood pressure increases significantly just after intubation but the increase was not significant after 10 minutes. There was no significant difference regarding laryngoscopy, vocal cord relaxation and response to intubation in both the groups. Overall intubating conditions in group A and B were excellent in 77.5% and 82.5% while good in 20% and17.5% patients respectively. Only one patient (2.5%) in group A showed poor intubating condition. Clinically acceptable intubating conditions (excellent & good) were comparable in both the groups. Conclusion: Rocuronium 0.6mg/kg provides clinically acceptable intubating conditions similar to succinylcholine 1.5mg/kg at 60 second during rapid sequence induction and intubation with minimum haemodynamic variations. |
Key Words: Rocuronium, succinylcholine, intubating condition, rapid sequence intubation.
Dr Ibemhal Heisnam
Associate Professor, Department of Anaesthesiology and Critical Care
Jawaharlal Nehru Institute of Medical Sciences Imphal: - 795005 Manipur
Mobile no: 9856153557, E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
