Title: Study of Patients with Non Alcoholic Fatty Liver Disease and its Association with Metabolic Syndrome in tertiary centre
Authors: Dr P.Asati, Dr P.Kukrele, Dr Sarita Jalodiya
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.16
Abstract
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NAFLD Nonalcoholic fatty liver disease (NAFLD) is emerging as an important cause of liver disease in India. NAFLD includes patient with simple steatosis, as also those with non alcoholic steatoheaptitis (NASH). NASH is more advanced stage of NAFLD and has a higher risk of progressing to liver cirrhosis or hepato cellular carcinoma[1].NAFLD frequently associated with metabolic syndrome, obesity, Type-2 diabetes mellitus and hyper lipidaemia are co-existing conditions frequently associated with NAFLD. Because of the strong association with various metabolic abnormalitites, NAFLD is now considered as a part of spectrum of metabolic syndrome. the present study is aimed to evaluate the clinical, biochemical profile in patients of NAFLD with varying degree of severity as diagnosed by ultrasonography and evaluate the association between the non-alcoholic fatty liver disease and the metabolic syndrome and its individual components as defined by the NCEP ATP III criteria. |
Results:51% of patients with NAFLD had metabolic syndrome and statistically significance was found in AST, waist circumference, lipid profile total cholesterol was significantly higher in grade III NAFLD which was significantly higher. AST ALT values were significantly higher among grade III NAFLD Cases (p value <0.001,<0.001 respectively.
